Detailed information NTG0281692

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: C9I27_RS03825
• Genome accession: NZ_CP028148
• Coordinates: 732256..733485 (+)
• Length: 409 a.a.
• NCBI ID: WP_002990162.1
• Uniprot ID: Q1JM77
• Organism: Streptococcus pyogenes strain TJ11-001
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 727256..738485

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C9I27_RS03800	-	727872..729149 (-)	1278	WP_002990172.1	hydroxymethylglutaryl-CoA reductase, degradative	-
C9I27_RS03805	-	729136..730311 (-)	1176	WP_002990170.1	hydroxymethylglutaryl-CoA synthase	-
C9I27_RS03810	-	730520..731359 (+)	840	WP_002990167.1	thymidylate synthase	-
C9I27_RS03815	-	731439..731936 (+)	498	WP_002984955.1	dihydrofolate reductase	-
C9I27_RS10140	-	731956..732126 (+)	171	WP_002990165.1	hypothetical protein	-
C9I27_RS03825	clpX	732256..733485 (+)	1230	WP_002990162.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
C9I27_RS03830	yihA	733495..734094 (+)	600	WP_002990160.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
C9I27_RS03835	-	734242..734985 (+)	744	WP_002984942.1	hypothetical protein	-
C9I27_RS03840	-	735043..737142 (-)	2100	WP_002990158.1	AAA family ATPase	-
C9I27_RS03845	rpiA	737520..738203 (+)	684	WP_002990155.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45036.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=281692 C9I27_RS03825 WP_002990162.1 732256..733485(+) (clpX) [Streptococcus pyogenes strain TJ11-001]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELSEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=281692 C9I27_RS03825 WP_002990162.1 732256..733485(+) (clpX) [Streptococcus pyogenes strain TJ11-001]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGTCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCTAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTTGAATTAGAATTTGATAA
AGCAGCTCTTGAAGCTATCGCAACTAAAGCGATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CAATGCTTGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

3D structure

• AlphaFold DB: Q1JM77

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575