Detailed information NTG0280910

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: D4I31_RS03320
• Genome accession: NZ_CP032908
• Coordinates: 685240..687822 (-)
• Length: 860 a.a.
• NCBI ID: WP_139534473.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain 23-A-EK1
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 680240..692822

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D4I31_RS03300	comB10	681186..682385 (-)	1200	WP_139534467.1	DNA type IV secretion system protein ComB10	Machinery gene
D4I31_RS03305	-	682382..683986 (-)	1605	WP_139534469.1	TrbG/VirB9 family P-type conjugative transfer protein	-
D4I31_RS03310	-	683983..685116 (-)	1134	WP_139534471.1	VirB8/TrbF family protein	-
D4I31_RS03315	-	685109..685243 (-)	135	WP_000738749.1	hypothetical protein	-
D4I31_RS03320	comB4	685240..687822 (-)	2583	WP_139534473.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
D4I31_RS03325	-	687822..688058 (-)	237	WP_139534474.1	hypothetical protein	-
D4I31_RS03330	comB3	688069..688332 (-)	264	WP_139534476.1	competence protein ComB	Machinery gene
D4I31_RS03335	comB2	688343..688627 (-)	285	WP_000736478.1	TrbC/VirB2 family protein	Machinery gene
D4I31_RS03340	-	688624..689103 (-)	480	WP_139534478.1	hypothetical protein	-
D4I31_RS03345	-	689207..689995 (-)	789	WP_139534480.1	integrase	-
D4I31_RS03350	-	690069..690488 (+)	420	WP_236635762.1	hypothetical protein	-
D4I31_RS03355	-	690576..691010 (+)	435	WP_139534482.1	hypothetical protein	-
D4I31_RS03360	-	691010..692131 (+)	1122	WP_201738180.1	DUF1542 domain-containing protein	-

Sequence

Protein

• Length: 860 a.a.
• Molecular weight: 98986.01 Da
• Isoelectric Point: 8.5663

>NTDB_id=280910 D4I31_RS03320 WP_139534473.1 685240..687822(-) (comB4) [Helicobacter pylori strain 23-A-EK1]
MFENALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNETHSNTSSKKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGIYNEGESFHINPFSLEDSASNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALRINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLCPT

Nucleotide

• Length: 2583 bp

>NTDB_id=280910 D4I31_RS03320 WP_139534473.1 685240..687822(-) (comB4) [Helicobacter pylori strain 23-A-EK1]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGTTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGATTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCTATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAGACCCATTCAAATACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGACAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTT
TCTTTTTTTCCTAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTGATCTTGTT
TGAGAAAAATAATACAGGTTTTAGAGCAAATTCATGGGGGGATATGCCATTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGACAT
ACCATGATTATTGGCGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGCGCTTTAAAATACCCTAA
CATTGACATTCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATGAAGGCG
AAAGCTTTCATATTAATCCTTTTTCATTAGAAGATAGCGCAAGTAACAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCCCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTCAGCAACCAAGAATTACCACTTCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAAGACTATTTAAAATCTTCTTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATGATGACGCTGG
GCTTTTAGCCTATTATGTCTTTCATAAAATGATTGATAGAGCCTTGAGAATCAATCGTGGGTTTTTGTGTTTTATTGATG
AGTTTAAGTCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTGATTGTTTTAGCCTTACAAGATATTAACCAGCTTAGTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCT
TATTAAGCATTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTTGCCCAACATGA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-504)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	47.087	97.791	0.46