Detailed information NTG0280909

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: C7J88_RS02290
• Genome accession: NZ_CP027848
• Coordinates: 482249..483223 (+)
• Length: 324 a.a.
• NCBI ID: WP_095116803.1
• Uniprot ID: A0A240C4G8
• Organism: Staphylococcus muscae strain ATCC 49910
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 477249..488223

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7J88_RS02260 (C7J88_02255)	-	478036..478590 (+)	555	WP_095116789.1	5-formyltetrahydrofolate cyclo-ligase	-
C7J88_RS02265 (C7J88_02260)	-	478592..480031 (+)	1440	WP_095116791.1	rhomboid family intramembrane serine protease	-
C7J88_RS02270 (C7J88_02265)	-	480033..480236 (+)	204	WP_095116793.1	YqgQ family protein	-
C7J88_RS02275 (C7J88_02270)	-	480233..481213 (+)	981	WP_095116795.1	ROK family glucokinase	-
C7J88_RS02280 (C7J88_02275)	-	481220..481531 (+)	312	WP_095116797.1	MTH1187 family thiamine-binding protein	-
C7J88_RS02285 (C7J88_02280)	-	481559..482182 (+)	624	WP_095116800.1	MBL fold metallo-hydrolase	-
C7J88_RS02290 (C7J88_02285)	comGA	482249..483223 (+)	975	WP_095116803.1	competence type IV pilus ATPase ComGA	Machinery gene
C7J88_RS02295 (C7J88_02290)	comGB	483192..484259 (+)	1068	WP_095116805.1	competence type IV pilus assembly protein ComGB	-
C7J88_RS02300 (C7J88_02295)	comGC	484271..484591 (+)	321	WP_095116807.1	competence type IV pilus major pilin ComGC	Machinery gene
C7J88_RS02305 (C7J88_02300)	comGD	484581..485012 (+)	432	WP_157728687.1	competence type IV pilus minor pilin ComGD	-
C7J88_RS10625 (C7J88_02310)	-	485199..485693 (+)	495	WP_095116813.1	competence type IV pilus minor pilin ComGF	-
C7J88_RS02325 (C7J88_02320)	-	485859..486383 (+)	525	WP_095116816.1	shikimate kinase	-
C7J88_RS02330 (C7J88_02325)	gcvT	486543..487634 (+)	1092	WP_095116818.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36727.08 Da
• Isoelectric Point: 6.1187

>NTDB_id=280909 C7J88_RS02290 WP_095116803.1 482249..483223(+) (comGA) [Staphylococcus muscae strain ATCC 49910]
MQFLLDTVLQHALSEGASDIHFIPSSDHVEVKLRVNDQLSLYDSLNLETYQRLLTLLKFQAGLDVSSRHRAQSGRYIYHF
KDLYYLRVSTLPINLGNESCVIRITPQYFQNIALENTEDICSLMEKKQGLILFSGPTGAGKSTLMYQMVLYAKQTLNLNV
ITIEDPVERLINGVTQISVNEKADITYNASLKAILRCDPDVILIGEIRDASIAHDVIQASLSGHLVLTTIHANDCQGVLL
RLIEMGVSKQDLLQATNLIVNQRLVTTTEQKRELVYETMLHNDIQHFFEHNFQLPESFSSLSDKLNLLKEQGVIDAATYR
KYRT

Nucleotide

• Length: 975 bp

>NTDB_id=280909 C7J88_RS02290 WP_095116803.1 482249..483223(+) (comGA) [Staphylococcus muscae strain ATCC 49910]
ATGCAGTTTTTATTGGATACCGTCCTACAACATGCATTGTCTGAAGGTGCATCCGATATACATTTTATTCCATCATCAGA
CCATGTTGAAGTAAAACTACGTGTCAATGACCAGTTATCATTATACGACTCATTAAATTTAGAGACATATCAGCGTTTAT
TAACACTATTAAAATTTCAAGCTGGTCTTGATGTATCTTCCAGACATCGTGCTCAAAGTGGGAGATACATCTATCATTTT
AAAGATTTATATTATTTACGTGTGTCAACTTTGCCCATTAATTTAGGCAATGAGAGTTGTGTTATTCGTATTACTCCACA
GTATTTTCAGAATATTGCACTGGAAAATACAGAGGATATATGCAGTTTAATGGAGAAGAAACAAGGTCTAATACTCTTTA
GCGGACCTACTGGTGCAGGCAAAAGTACGCTTATGTATCAAATGGTTCTCTATGCAAAGCAAACACTTAATCTTAATGTC
ATCACGATTGAAGATCCAGTCGAGAGGCTTATTAATGGTGTGACACAAATATCTGTTAATGAGAAGGCAGATATTACATA
TAATGCTTCACTAAAAGCAATCTTGCGCTGTGACCCTGATGTCATACTTATCGGCGAAATTCGCGATGCATCAATAGCTC
ATGATGTGATACAAGCCAGCTTGAGTGGACATCTAGTGCTCACAACAATTCATGCTAATGATTGTCAAGGCGTTTTGTTA
CGCTTAATCGAAATGGGCGTATCAAAACAAGATTTACTACAAGCTACTAATTTAATTGTAAATCAACGTCTTGTCACCAC
AACCGAACAAAAAAGAGAACTTGTTTATGAAACGATGTTACACAATGATATACAGCACTTTTTTGAACATAACTTTCAAT
TACCAGAATCATTTTCTAGCTTATCGGATAAACTTAATTTGTTGAAAGAACAGGGGGTCATCGATGCGGCAACTTATAGA
AAATATCGAACATAG

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (8-266)

3D structure

• AlphaFold DB: A0A240C4G8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	59.443	99.691	0.593
comGA	Staphylococcus aureus N315	59.443	99.691	0.593