Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   HSM_RS05535 Genome accession   NC_010519
Coordinates   1229521..1230306 (-) Length   261 a.a.
NCBI ID   WP_012340257.1    Uniprot ID   A0A9Q7E7G6
Organism   Histophilus somni 2336     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1224521..1235306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSM_RS05505 (HSM_1064) - 1224641..1225504 (-) 864 WP_012340252.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  HSM_RS05510 (HSM_1065) aroB 1225511..1226599 (-) 1089 WP_012340253.1 3-dehydroquinate synthase -
  HSM_RS05515 (HSM_1066) aroK 1226619..1227146 (-) 528 WP_012340254.1 shikimate kinase AroK -
  HSM_RS05520 (HSM_1067) comE 1227328..1228461 (-) 1134 WP_012340255.1 type IV pilus secretin PilQ Machinery gene
  HSM_RS05525 (HSM_1068) - 1228477..1228974 (-) 498 WP_011609266.1 hypothetical protein -
  HSM_RS05530 (HSM_1069) - 1228978..1229517 (-) 540 WP_012340256.1 PilN domain-containing protein -
  HSM_RS05535 (HSM_1070) comA 1229521..1230306 (-) 786 WP_012340257.1 hypothetical protein Machinery gene
  HSM_RS05540 (HSM_1071) - 1230431..1232971 (+) 2541 WP_012340258.1 penicillin-binding protein 1A -
  HSM_RS05545 (HSM_1072) - 1233031..1233876 (+) 846 WP_012340259.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 31292.78 Da        Isoelectric Point: 7.1316

>NTDB_id=28087 HSM_RS05535 WP_012340257.1 1229521..1230306(-) (comA) [Histophilus somni 2336]
MRPNKKTANILQIGIHRQDEQWQFLWFDEQKQPHFLTKNDNPPLKLSDLTPQFAKNICTWIACLPNQHVWVKTIILTQKL
NEQECQQQCNLIIENELPTDFDDIWYDYQYKELTQGAKLAIYVVRKQTAQNYVHRFFPIKINTLDCLSNSLLRAFHYFHP
QKEKMETLYLYQDRNGCIAIQEIGQQTIVLQKNDKNITALYQEFCQRFNCQPQHVWCYCEKNEQQNITHKWNIINTELPF
IALGNALWGRHELYQITELKE

Nucleotide


Download         Length: 786 bp        

>NTDB_id=28087 HSM_RS05535 WP_012340257.1 1229521..1230306(-) (comA) [Histophilus somni 2336]
ATGAGACCTAACAAAAAAACAGCAAATATTTTACAAATTGGTATTCATAGACAAGATGAACAATGGCAATTCCTCTGGTT
TGATGAACAAAAACAACCGCACTTTTTAACTAAAAACGATAATCCCCCTCTTAAACTATCTGATTTGACACCACAATTCG
CAAAGAATATCTGCACATGGATAGCCTGTTTACCCAATCAGCACGTCTGGGTAAAAACAATCATATTGACGCAAAAGTTA
AATGAGCAAGAATGCCAACAACAATGTAACTTAATCATAGAAAATGAATTGCCGACAGATTTCGATGATATTTGGTACGA
CTACCAATATAAAGAATTAACACAAGGTGCAAAACTGGCTATCTACGTTGTTAGAAAACAAACAGCTCAAAATTATGTGC
ATCGTTTTTTCCCTATAAAAATTAATACATTAGATTGCTTAAGTAATAGCCTACTACGAGCATTCCATTATTTTCACCCC
CAAAAAGAAAAGATGGAAACATTATATTTATATCAGGATCGTAACGGCTGTATAGCAATACAAGAAATCGGACAACAAAC
AATCGTTCTACAAAAAAATGACAAAAATATTACCGCACTTTATCAAGAATTCTGCCAACGTTTTAACTGCCAACCTCAAC
ACGTTTGGTGCTATTGTGAAAAAAATGAACAACAAAATATCACTCATAAATGGAACATCATTAATACCGAATTGCCTTTT
ATTGCTTTAGGAAATGCTCTTTGGGGAAGACATGAACTCTATCAAATAACGGAATTAAAGGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9Q7E7G6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Haemophilus influenzae 86-028NP

40.467

98.467

0.398
  comA Haemophilus influenzae Rd KW20

39.3

98.467

0.387

Multiple sequence alignment