Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   C7V31_RS12990 Genome accession   NZ_CP032892
Coordinates   2003366..2004022 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain SCEC020022     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1998366..2009022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7V31_RS12965 (C7V31_12965) dcyD 1999246..2000232 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  C7V31_RS12970 (C7V31_12970) tcyL 2000247..2000915 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  C7V31_RS12975 (C7V31_12975) tcyN 2000912..2001664 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  C7V31_RS12980 (C7V31_12980) sdiA 2001894..2002616 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  C7V31_RS12985 (C7V31_12985) yecF 2002683..2002907 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  C7V31_RS27315 yecU 2002894..2003070 (-) 177 WP_000590347.1 protein YecU -
  C7V31_RS28290 - 2003153..2003224 (-) 72 Protein_1909 transcriptional regulator -
  C7V31_RS12990 (C7V31_12990) letA 2003366..2004022 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  C7V31_RS12995 (C7V31_12995) uvrC 2004019..2005851 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  C7V31_RS13000 (C7V31_13000) pgsA 2005908..2006456 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  C7V31_RS13020 (C7V31_13020) - 2007152..2007892 (-) 741 Protein_1913 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=280431 C7V31_RS12990 WP_000611335.1 2003366..2004022(+) (letA) [Escherichia coli strain SCEC020022]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=280431 C7V31_RS12990 WP_000611335.1 2003366..2004022(+) (letA) [Escherichia coli strain SCEC020022]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment