Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D8Z74_RS10755 Genome accession   NZ_CP032793
Coordinates   2125114..2125770 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain NZRM3614     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2120114..2130770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D8Z74_RS10720 (D8Z74_11000) dcyD 2120993..2121979 (+) 987 WP_001128225.1 D-cysteine desulfhydrase -
  D8Z74_RS10725 (D8Z74_11005) tcyL 2121994..2122662 (+) 669 WP_001158226.1 cystine ABC transporter permease -
  D8Z74_RS10730 (D8Z74_11010) tcyN 2122659..2123411 (+) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  D8Z74_RS10735 (D8Z74_11015) sdiA 2123641..2124363 (+) 723 WP_001154288.1 transcriptional regulator SdiA -
  D8Z74_RS10740 (D8Z74_11020) yecF 2124431..2124655 (-) 225 WP_000106479.1 DUF2594 family protein YecF -
  D8Z74_RS10745 yecU 2124642..2124818 (-) 177 WP_001302050.1 protein YecU -
  D8Z74_RS28620 (D8Z74_11025) - 2124856..2124972 (-) 117 WP_001302039.1 hypothetical protein -
  D8Z74_RS10755 (D8Z74_11030) letA 2125114..2125770 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  D8Z74_RS10760 (D8Z74_11035) uvrC 2125767..2127599 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  D8Z74_RS10765 (D8Z74_11040) pgsA 2127656..2128204 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  D8Z74_RS10785 (D8Z74_11060) yecA 2128853..2129518 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=278140 D8Z74_RS10755 WP_000611328.1 2125114..2125770(+) (letA) [Escherichia coli strain NZRM3614]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=278140 D8Z74_RS10755 WP_000611328.1 2125114..2125770(+) (letA) [Escherichia coli strain NZRM3614]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment