Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D8Z75_RS12915 Genome accession   NZ_CP032791
Coordinates   2576446..2577102 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain NZRM4165     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2571446..2582102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D8Z75_RS12875 (D8Z75_13160) - 2571446..2572582 (-) 1137 WP_032161583.1 IS30-like element IS30 family transposase -
  D8Z75_RS12880 - 2572524..2572718 (-) 195 WP_115801851.1 hypothetical protein -
  D8Z75_RS12885 - 2572739..2573020 (-) 282 WP_001303543.1 hypothetical protein -
  D8Z75_RS12905 (D8Z75_13185) pgsA 2574012..2574560 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  D8Z75_RS12910 (D8Z75_13190) uvrC 2574617..2576449 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  D8Z75_RS12915 (D8Z75_13195) letA 2576446..2577102 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  D8Z75_RS28745 (D8Z75_13200) - 2577244..2577360 (+) 117 WP_001302039.1 hypothetical protein -
  D8Z75_RS12925 yecU 2577398..2577574 (+) 177 WP_001302050.1 protein YecU -
  D8Z75_RS12930 (D8Z75_13205) yecF 2577561..2577785 (+) 225 WP_000106479.1 DUF2594 family protein YecF -
  D8Z75_RS12935 (D8Z75_13210) sdiA 2577853..2578575 (-) 723 WP_001154288.1 transcriptional regulator SdiA -
  D8Z75_RS12940 (D8Z75_13215) tcyN 2578805..2579557 (-) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  D8Z75_RS12945 (D8Z75_13220) tcyL 2579554..2580222 (-) 669 WP_001158226.1 cystine ABC transporter permease -
  D8Z75_RS12950 (D8Z75_13225) dcyD 2580237..2581223 (-) 987 WP_001128225.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=278063 D8Z75_RS12915 WP_000611328.1 2576446..2577102(-) (letA) [Escherichia coli strain NZRM4165]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=278063 D8Z75_RS12915 WP_000611328.1 2576446..2577102(-) (letA) [Escherichia coli strain NZRM4165]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482