Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   D8S76_RS07155 Genome accession   NZ_CP032699
Coordinates   1387054..1387695 (-) Length   213 a.a.
NCBI ID   WP_023079253.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY155     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1382054..1392695
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D8S76_RS07130 (D8S76_07125) comFA/cflA 1382140..1383465 (-) 1326 WP_115224631.1 DEAD/DEAH box helicase Machinery gene
  D8S76_RS07135 (D8S76_07130) - 1383521..1384153 (+) 633 WP_032465870.1 YigZ family protein -
  D8S76_RS07140 (D8S76_07135) cysK 1384281..1385222 (+) 942 WP_023079244.1 cysteine synthase A -
  D8S76_RS07145 (D8S76_07140) - 1385240..1385617 (-) 378 WP_002983674.1 S1 RNA-binding domain-containing protein -
  D8S76_RS07150 (D8S76_07145) - 1385617..1387017 (-) 1401 WP_023079249.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  D8S76_RS07155 (D8S76_07150) vraR 1387054..1387695 (-) 642 WP_023079253.1 response regulator transcription factor Regulator
  D8S76_RS07160 (D8S76_07155) - 1387688..1388692 (-) 1005 WP_002991890.1 sensor histidine kinase -
  D8S76_RS07165 (D8S76_07160) liaF 1388689..1389381 (-) 693 WP_011054833.1 cell wall-active antibiotics response protein LiaF -
  D8S76_RS07170 (D8S76_07165) pknB 1389504..1391402 (-) 1899 WP_023079250.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  D8S76_RS07175 (D8S76_07170) - 1391399..1392139 (-) 741 WP_002983660.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23781.46 Da        Isoelectric Point: 5.1641

>NTDB_id=277649 D8S76_RS07155 WP_023079253.1 1387054..1387695(-) (vraR) [Streptococcus pyogenes strain TSPY155]
MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDLALTLKPDVLVMDLVMPELGGVEATLEVLKKWKEAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=277649 D8S76_RS07155 WP_023079253.1 1387054..1387695(-) (vraR) [Streptococcus pyogenes strain TSPY155]
ATGAGTAAGATAAAAGTGATATTGGTCGATGATCATGAAATGGTCCGCATGGGACTCAAGAGTTTTTTGAATTTACAAGC
TGATATTGATGTCGTTGGTGAGGCCTCTAATGGACGTGAAGGGGTTGATTTGGCATTGACTTTGAAGCCAGATGTTTTGG
TTATGGATCTAGTGATGCCAGAGTTAGGCGGTGTTGAGGCAACTTTAGAAGTCCTAAAAAAATGGAAAGAGGCTAAGGTA
CTTGTGTTAACTTCCTATCTAGATAATGAAAAGATATACCCTGTCATTGATGCAGGAGCGAAGGGTTATATGTTAAAAAC
ATCGAGTGCGGCTGAAATTTTAAATGCCATTCGCAAGGTTTCAAAGGGAGAGTTAGCTATTGAAACAGAAGTTGACAAAA
AAATTAAGGCGCATGATCAACACCCTGACTTGCATGAGGAACTAACAGCGCGTGAGTATGACATTTTACACCTTTTAGCT
AAAGGGTATGATAATCAGACCATCGCTGATGAACTCTTTATTTCCTTAAAAACCGTCAAAACACATGTGTCCAATATTCT
AGCCAAGTTAGAAGTTGATGACCGAACCCAAGCGGTTGTCTATGCTTTTCGACATCATTTAGTCCCCCAAGACGATAATT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.913

96.714

0.512
  degU Bacillus subtilis subsp. subtilis str. 168

36.283

100

0.385