Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D7U33_RS09815 Genome accession   NZ_CP032679
Coordinates   1994708..1995364 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli str. K-12 substr. MG1655 strain K-12     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1989708..2000364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7U33_RS09785 (D7U33_09940) yecA 1990959..1991624 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  D7U33_RS09805 (D7U33_09960) pgsA 1992274..1992822 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  D7U33_RS09810 (D7U33_09965) uvrC 1992879..1994711 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  D7U33_RS09815 (D7U33_09970) letA 1994708..1995364 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  D7U33_RS22730 - 1995506..1995577 (+) 72 Protein_1949 transcriptional regulator -
  D7U33_RS09820 yecU 1995660..1995836 (+) 177 WP_000590347.1 protein YecU -
  D7U33_RS09825 (D7U33_09975) yecF 1995823..1996047 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  D7U33_RS09830 (D7U33_09980) sdiA 1996115..1996837 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  D7U33_RS09835 (D7U33_09985) tcyN 1997067..1997819 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  D7U33_RS09840 (D7U33_09990) tcyL 1997816..1998484 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  D7U33_RS09845 (D7U33_09995) dcyD 1998499..1999485 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=277527 D7U33_RS09815 WP_000611335.1 1994708..1995364(-) (letA) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=277527 D7U33_RS09815 WP_000611335.1 1994708..1995364(-) (letA) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486