Detailed information NTG0027631

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SPH_RS10425
• Genome accession: NC_010380
• Coordinates: 1965932..1966831 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904865.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae Hungary19A-6
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1960932..1971831

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPH_RS10400 (SPH_2126)	rsmA	1961268..1962140 (-)	873	WP_001216877.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
SPH_RS10405 (SPH_2127)	-	1962271..1962579 (-)	309	WP_000333257.1	hypothetical protein	-
SPH_RS10410 (SPH_2128)	-	1962572..1963213 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
SPH_RS10415 (SPH_2129)	-	1963215..1965245 (-)	2031	WP_000825270.1	bacteriocin-associated integral membrane family protein	-
SPH_RS10420 (SPH_2130)	-	1965322..1965618 (-)	297	WP_000815393.1	lactococcin 972 family bacteriocin	-
SPH_RS10425 (SPH_2131)	comR	1965932..1966831 (-)	900	WP_000904865.1	helix-turn-helix domain-containing protein	Regulator
SPH_RS10430 (SPH_2132)	rnmV	1966903..1967463 (-)	561	WP_000664448.1	ribonuclease M5	-
SPH_RS10435 (SPH_2133)	-	1967463..1968236 (-)	774	WP_000575635.1	TatD family hydrolase	-
SPH_RS10440 (SPH_2134)	-	1968541..1969440 (-)	900	WP_000226470.1	DUF1542 domain-containing protein	-
SPH_RS10445 (SPH_2135)	rpmH	1969724..1969858 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
SPH_RS10450 (SPH_2136)	-	1970003..1971217 (-)	1215	WP_000666465.1	pyridoxal phosphate-dependent aminotransferase	-
SPH_RS10455 (SPH_2137)	-	1971373..1971666 (-)	294	WP_000977364.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35175.08 Da
• Isoelectric Point: 5.2018

>NTDB_id=27631 SPH_RS10425 WP_000904865.1 1965932..1966831(-) (comR) [Streptococcus pneumoniae Hungary19A-6]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=27631 SPH_RS10425 WP_000904865.1 1965932..1966831(-) (comR) [Streptococcus pneumoniae Hungary19A-6]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

• Helix-turn-helix (HTH_3) (7-59)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	38.095	98.328	0.375
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368