Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   APL_RS09085 Genome accession   NC_009053
Coordinates   1942973..1944127 (+) Length   384 a.a.
NCBI ID   WP_009875464.1    Uniprot ID   A3N310
Organism   Actinobacillus pleuropneumoniae serovar 5b str. L20     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1937973..1949127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APL_RS09050 (APL_1706) - 1938088..1938826 (+) 739 Protein_1736 hypothetical protein -
  APL_RS09055 - 1938950..1939138 (-) 189 WP_005599189.1 hypothetical protein -
  APL_RS09060 (APL_1707) - 1939172..1939606 (+) 435 WP_009875461.1 factor H binding protein domain-containing protein -
  APL_RS11080 - 1939908..1941149 (+) 1242 Protein_1739 surface lipoprotein assembly modifier -
  APL_RS09075 (APL_1710) rfaD 1941209..1942135 (-) 927 WP_005599195.1 ADP-glyceromanno-heptose 6-epimerase -
  APL_RS09080 (APL_1711) def 1942275..1942787 (-) 513 WP_005599196.1 peptide deformylase -
  APL_RS09085 (APL_1712) dprA 1942973..1944127 (+) 1155 WP_009875464.1 DNA-processing protein DprA Machinery gene
  APL_RS09090 (APL_1713) - 1944171..1946177 (-) 2007 WP_011848643.1 OPT family oligopeptide transporter -
  APL_RS09095 (APL_1714) - 1946399..1947754 (-) 1356 WP_009875466.1 PTS ascorbate transporter subunit IIC -
  APL_RS09100 (APL_1715) - 1947763..1948035 (-) 273 WP_005599206.1 PTS sugar transporter subunit IIB -
  APL_RS09105 (APL_1716) secE 1948338..1948751 (+) 414 WP_011848644.1 preprotein translocase subunit SecE -

Sequence

Protein


Download         Length: 384 a.a.        Molecular weight: 42831.05 Da        Isoelectric Point: 5.4205

>NTDB_id=27631 APL_RS09085 WP_009875464.1 1942973..1944127(+) (dprA) [Actinobacillus pleuropneumoniae serovar 5b str. L20]
MSQADLLKLLQIPQLGAQRIARLLSEVDFAQFCQYDKRQLQQIGWNEKQIQRWFNPEMRWIDNALTWAERPNQHLLSLFD
EEYPFLLRQISTAPPVLFVRGSLSSLSLPQIAIVGSRDFSAYGEYWAGYFSEQLVKHHLAVTSGLAIGIDGFCHQRAVAE
QGITIAVLGSGLDQVYPARHKKLAEQIVESGGALVSEFFPNQPPLAENFPRRNRIISGLSLGTLVVEATLNSGSLITARY
ALEQGREVFALPNSVQNPYAQGCHKLIKEGAVLTETIEDILQAIQYQLPDQPWQQALFEPPQAVENAQFFTKADVPNKVN
HLAKKLPELTACQQQIVAHISLEPISIDDLAKATSLEVETLLVELLGLELLSVIKQVSGGYVRQ

Nucleotide


Download         Length: 1155 bp        

>NTDB_id=27631 APL_RS09085 WP_009875464.1 1942973..1944127(+) (dprA) [Actinobacillus pleuropneumoniae serovar 5b str. L20]
ATGTCTCAGGCTGATTTACTGAAATTATTGCAGATTCCGCAACTGGGGGCGCAGCGCATTGCTCGTCTGTTATCCGAAGT
GGATTTTGCCCAATTTTGCCAATATGACAAACGCCAATTACAACAAATTGGTTGGAACGAGAAACAGATTCAACGCTGGT
TCAATCCGGAAATGCGTTGGATTGATAATGCTCTCACGTGGGCGGAGCGGCCGAATCAACACTTATTGAGCTTATTTGAT
GAGGAATATCCGTTTTTATTACGGCAAATCAGCACCGCACCGCCGGTGTTATTTGTGCGAGGTTCGCTAAGCAGTTTGAG
CTTGCCGCAAATTGCGATTGTCGGTAGTCGAGACTTTTCCGCCTACGGAGAATACTGGGCGGGCTATTTTAGCGAGCAAT
TGGTTAAACATCATTTGGCGGTTACTAGCGGACTTGCAATCGGCATAGACGGTTTTTGCCATCAGCGAGCGGTAGCGGAA
CAGGGTATTACGATTGCTGTGTTGGGCAGCGGTTTAGATCAAGTCTATCCGGCAAGGCACAAAAAATTGGCGGAGCAAAT
TGTCGAAAGCGGCGGGGCGTTAGTGTCGGAATTTTTTCCGAATCAACCGCCGCTTGCCGAAAATTTCCCTCGTCGTAATC
GCATTATCAGCGGTTTGTCACTCGGTACGTTAGTGGTGGAAGCCACATTAAATAGCGGTTCGCTGATTACCGCCCGTTAT
GCGTTGGAACAAGGGCGAGAAGTGTTTGCATTACCGAATTCGGTACAAAATCCGTATGCACAAGGCTGTCATAAACTGAT
CAAAGAAGGGGCGGTTTTAACCGAAACGATAGAGGATATTTTACAGGCAATTCAATATCAACTGCCGGATCAGCCTTGGC
AACAGGCTCTGTTTGAACCGCCACAAGCGGTTGAAAACGCACAATTTTTTACAAAAGCAGATGTGCCGAATAAGGTCAAT
CATCTTGCAAAAAAATTGCCGGAATTGACCGCTTGTCAGCAACAAATTGTGGCGCATATTAGTCTTGAACCGATTTCGAT
TGACGATTTGGCTAAGGCGACTTCATTGGAGGTGGAAACACTGTTAGTCGAGTTACTGGGTTTGGAATTATTAAGTGTGA
TTAAGCAGGTAAGCGGCGGTTATGTCAGACAATAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(69-274)

DprA winged helix domain (DprA_WH)

(325-380)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3N310

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Glaesserella parasuis strain SC1401

75.198

98.698

0.742
  dprA Vibrio campbellii strain DS40M4

46.719

99.219

0.464
  dprA Haemophilus influenzae Rd KW20

49.28

90.365

0.445
  dprA Vibrio cholerae strain A1552

41.86

100

0.422
  dprA Legionella pneumophila strain ERS1305867

37.598

99.74

0.375

Multiple sequence alignment