Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/comE1   Type   Machinery gene
Locus tag   APL_RS07435 Genome accession   NC_009053
Coordinates   1607480..1607824 (+) Length   114 a.a.
NCBI ID   WP_005599904.1    Uniprot ID   A3N254
Organism   Actinobacillus pleuropneumoniae serovar 5b str. L20     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1602480..1612824
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APL_RS07410 (APL_1401) rpsL 1602612..1602986 (-) 375 WP_005543325.1 30S ribosomal protein S12 -
  APL_RS07415 (APL_1402) rfaC 1603108..1604067 (-) 960 WP_011848582.1 lipopolysaccharide heptosyltransferase RfaC -
  APL_RS07420 (APL_1403) waaF 1604143..1605180 (-) 1038 WP_009875545.1 lipopolysaccharide heptosyltransferase II -
  APL_RS07425 (APL_1404) - 1605262..1605666 (-) 405 WP_005599908.1 MliC family protein -
  APL_RS07430 (APL_1405) - 1605788..1607179 (-) 1392 WP_005605242.1 LysM-like peptidoglycan-binding domain-containing protein -
  APL_RS07435 (APL_1406) comEA/comE1 1607480..1607824 (+) 345 WP_005599904.1 ComEA family DNA-binding protein Machinery gene
  APL_RS07440 (APL_1407) asd 1607975..1608868 (+) 894 WP_005612934.1 archaetidylserine decarboxylase -
  APL_RS07445 (APL_1408) gshAB 1609024..1611297 (+) 2274 WP_009875544.1 bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB -
  APL_RS07450 (APL_1409) - 1611389..1612009 (-) 621 WP_011848583.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 114 a.a.        Molecular weight: 12446.30 Da        Isoelectric Point: 10.2030

>NTDB_id=27627 APL_RS07435 WP_005599904.1 1607480..1607824(+) (comEA/comE1) [Actinobacillus pleuropneumoniae serovar 5b str. L20]
MKKFARFSISFIIALLSADSIAKPNNPPVSEPTPVVQQMTTTNKTADKQNQVNINTADAAEIKSKLVGIGEKKAQAIVDY
RTKNGAFITIEQLTEVSGIGKATLEKNRERITLE

Nucleotide


Download         Length: 345 bp        

>NTDB_id=27627 APL_RS07435 WP_005599904.1 1607480..1607824(+) (comEA/comE1) [Actinobacillus pleuropneumoniae serovar 5b str. L20]
ATGAAAAAATTTGCCCGATTTAGTATTAGCTTCATCATTGCATTGTTATCCGCCGATTCAATCGCAAAGCCTAATAATCC
GCCCGTTTCCGAACCGACTCCCGTAGTTCAACAAATGACAACAACGAACAAAACTGCCGATAAACAAAATCAAGTGAATA
TCAATACGGCGGATGCAGCGGAAATTAAATCCAAACTGGTGGGAATCGGTGAGAAAAAAGCACAAGCGATTGTCGATTAC
CGCACTAAAAACGGTGCTTTTATTACGATAGAACAACTAACGGAAGTCTCCGGAATCGGTAAAGCGACACTAGAGAAAAA
TCGCGAACGCATCACGTTAGAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(48-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3N254

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/comE1 Glaesserella parasuis strain SC1401

58.261

100

0.588
  comE1/comEA Haemophilus influenzae Rd KW20

47.115

91.228

0.43

Multiple sequence alignment