Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   SPH_RS05945 Genome accession   NC_010380
Coordinates   1128055..1131705 (+) Length   1216 a.a.
NCBI ID   WP_000767219.1    Uniprot ID   B1IBR6
Organism   Streptococcus pneumoniae Hungary19A-6     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1123055..1136705
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPH_RS12580 (SPH_1223) - 1123066..1123512 (-) 447 WP_001811697.1 tyrosine-type recombinase/integrase -
  SPH_RS12585 - 1123412..1124257 (-) 846 Protein_1142 IS630 family transposase -
  SPH_RS13230 - 1124428..1124583 (+) 156 Protein_1143 diacylglycerol kinase family lipid kinase -
  SPH_RS05940 (SPH_1225) rexB 1124783..1128058 (+) 3276 WP_000772379.1 ATP-dependent nuclease subunit B Machinery gene
  SPH_RS05945 (SPH_1226) rexA 1128055..1131705 (+) 3651 WP_000767219.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  SPH_RS05950 (SPH_1228) - 1131920..1133096 (+) 1177 Protein_1146 hypothetical protein -

Sequence

Protein


Download         Length: 1216 a.a.        Molecular weight: 140230.89 Da        Isoelectric Point: 5.3479

>NTDB_id=27588 SPH_RS05945 WP_000767219.1 1128055..1131705(+) (rexA) [Streptococcus pneumoniae Hungary19A-6]
MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNILVSASAGSGKTFVMAERILDQLARGVEISQLFISTFT
VKAANELKERLEKKISKKIQETDDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWLSDSFLKGFEKADFTSEKEKLTE
QIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLILDEIGSLNQESDSQAYQAVLAHVVAISKEKNGRALTNASRKADL
KPLADAYNEERKTQFAKLGQLSDQITILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADISHYTIEILE
NFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNEKFQRYAQNPQEGKLIL
LKENFRSSSEVLSATNDVFERLMDQEVGEINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMR
LVIKEILKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLDTLRVIHNPLQDYALVA
LMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMASSQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIW
KIYNDRFYYDYVGALPNGPARQANLYALALRADQFEKSNFKGLPRFIRMIDQVLEAQHDLASVVVAPPKDAVELMTIHKS
KGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIKLSIPSLTYRQNEEELQLASYSEQM
RLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAKNGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTRE
AIGELETKSPLQDSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGVEIAGQGQSVG
KKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLKQVQTSQAVRDKINLDKILAFFDTVLGQEILAN
TDHLYREQPFSMLKRDQKSQEDFVVRGILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIE
KYLILLGKDEVQVVKV

Nucleotide


Download         Length: 3651 bp        

>NTDB_id=27588 SPH_RS05945 WP_000767219.1 1128055..1131705(+) (rexA) [Streptococcus pneumoniae Hungary19A-6]
ATGAAGCTTATTCCCTTTTTAAGTGAGGAGGAGATTCAAAAACTGCAAGAAGCAGAAGCAAATTCGAGCAAGGAACAGAA
GAAAACTGCCGAGCAAATCGAAGCTATCTACACTTCTGGCCAGAATATCCTGGTCTCAGCATCGGCTGGTTCTGGAAAGA
CCTTTGTCATGGCAGAGCGCATTCTGGACCAATTGGCGCGTGGTGTCGAAATTTCTCAACTCTTTATCTCAACCTTTACC
GTCAAGGCTGCAAATGAACTTAAAGAACGTTTAGAGAAAAAAATCAGCAAGAAAATCCAAGAAACAGATGATGTCGACCT
CAAACAACACTTGGGACGCCAGTTGGCAGACCTACCAAACGCTGCCATCGGAACCATGGACTCTTTCACACAAAAATTCC
TTGGCAAACATGGTTATCTGCTTGATATTGCACCTAATTTCCGTATTTTACAAAACCAAAGCGAGCAACTTCTTCTCGAA
AACGAAGTCTTTCATGAGGTCTTTGAAGCGCATTACCAAGGTAAACAGAAAGAGACCTTTAGTCATTTGCTGAAAAACTT
TGCTGGGCGTGGCAAGGACGAACGGGGTCTGCGCCAGCAGGTCTATAAAATCTATGACTTCCTCCAATCCACCAGCAATC
CTCAAAAGTGGCTGAGTGACTCTTTCCTCAAAGGCTTTGAGAAAGCTGATTTTACCAGTGAAAAAGAAAAACTGACTGAG
CAAATCAAACAAGCCCTTTGGGATTTGGAAAGCTTTTTCCGTTACCATCTGGATAACGATGCCAAGGAGTTTGCAAAGGC
TGCCTATTTAGAAAATGTTCAGTTAATTCTGGATGAAATTGGCTCCCTAAATCAGGAGTCCGATAGTCAGGCTTATCAGG
CAGTGCTTGCGCATGTTGTCGCCATCTCTAAGGAGAAAAACGGTCGAGCTCTGACTAATGCCAGCCGTAAGGCTGATTTG
AAGCCCCTGGCTGATGCCTACAACGAAGAGAGAAAGACCCAGTTTGCTAAACTAGGACAATTATCAGACCAGATAACCAT
TCTCGACTATCAAGAACGTTATCATGGAGACACTTGGAAACTAGCTAAAACCTTCCAATCTTTCATGAGCGATTTTGTGG
AGGCTTATCGTCAGAGAAAACGACAGGAAAATGCCTTTGAATTCGCTGATATCAGCCATTACACCATTGAGATTTTAGAG
AATTTCCCACAAGTTCGTGAGTCTTATCAGGAGCGCTTCCATGAAGTCATGGTCGATGAGTATCAGGATACCAACCATAT
TCAAGAACGAATGCTGGAATTGTTGTCTAATGGCCACAATCGCTTTATGGTGGGAGATATCAAGCAATCCATCTATCGTT
TCCGTCAGGCAGACCCGCAGATTTTCAATGAGAAATTCCAACGCTATGCGCAAAATCCTCAAGAAGGCAAGCTCATTCTC
CTCAAGGAAAATTTCCGTAGTAGTTCAGAAGTGCTGTCAGCAACCAATGATGTCTTTGAACGTCTCATGGACCAAGAGGT
CGGCGAAATCAACTATGATAACAAGCACCAGCTTGTTTTTGCCAATACCAAACTGACTCCCAATCCAGACAACAAGGCAG
AATTTCTCCTCTACGACAAGGATGATACAGGTGAGGAAGAAGAGAGTCAAACAGAAACGAAACTAACAGGCGAAATGCGC
TTAGTTATCAAGGAGATTCTGAAACTTCATCAGGAAAAAGGTGTTGCCTTTAAGGAAATTGCCCTTCTAACCTCCAGCCG
CAGTCGTAATGACCAGATTCTCCTCGCCCTGTCTGAGTACGGGATTCCTGTCAAAACTGACGGAGAGCAAAACAATTATC
TCCAATCCCTAGAAGTGCAAGTCATGCTAGACACTCTTCGTGTCATTCACAATCCCCTGCAAGACTACGCCTTGGTTGCC
CTTATGAAGTCTCCAATGTTTGGTTTTGATGAGGATGAGCTAGCACGTTTGTCCCTTCAGAAAGCAGAGGATAAAGTCCA
CGAAAATCTCTATGAGAAACTGGTCAATGCACAAAAAATGGCAAGTAGTCAAAAAGGCTTGATTCACACAGCTCTAGCTG
AAAAACTAAAGCAATTCATGGATATCCTAGCTTCTTGGCGCTTGTATGCCAAAACCCATTCTCTCTATGACTTGATTTGG
AAGATTTACAACGACCGTTTTTATTATGACTATGTTGGGGCTTTGCCGAATGGTCCTGCTAGGCAGGCCAATCTCTATGC
CCTAGCACTGCGTGCTGATCAATTTGAAAAGAGCAATTTCAAAGGTTTGCCGCGTTTTATTCGTATGATTGACCAAGTCT
TAGAAGCCCAGCACGATTTGGCAAGCGTGGTCGTCGCACCGCCAAAAGATGCAGTAGAGCTCATGACCATCCACAAGAGT
AAAGGGCTGGAGTTTCCTTACGTCTTTATCCTCAATATGGATCAAGATTTCAACAAGCAAGACTCTATGTCAGAAGTCAT
TCTCAGTCGTCAGAATGGTCTTGGTGTCAAATATATTGCCAAGATGGAGACAGGGGCAGTAGAAGACCACTATCCTAAAA
CCATCAAACTCTCCATTCCTAGTCTGACCTATAGGCAGAACGAAGAGGAATTACAGCTAGCAAGCTATTCTGAGCAGATG
CGTTTGCTGTATGTTGCTATGACGCGGGCTGAGAAAAAGCTCTATCTTGTCGGCAAGGGTTCTCGTGAAAAGCTGGAATC
CAAGGAATACCCAGCAGCCAAAAATGGGAAACTAAATAGCAATACTAGACTGCAAGCACGGAATTTCCAAGATTGGCTTT
GGGCTATCAGTAAAGTGTTTACTAAGGACAAGCTCAACTTTAGTTATCGTTTTATTGGCGAAGATCAGTTGACCAGAGAA
GCTATCGGAGAGTTGGAAACCAAGAGTCCTCTCCAAGATAGCTCCCAAGCAGACAATCGTCAGTCAGATACCATCAAAGA
AGCTCTGGAAATGCTGAAGGAGGTGGAAGTTTATAATACTCTTCACCGCGCAGCTATTGAACTTCCTAGTGTTCAAACCC
CAAGTCAAATCAAGAAATTCTACGAACCAGTTATGGATATGGAAGGTGTCGAGATTGCTGGTCAAGGTCAGTCAGTAGGC
AAGAAAATCAGCTTCGATTTGCCAGATTTTTCAACCAAAGAAAAGGTAACTGGAGCTGAGATTGGTAGTGCTACTCACGA
ACTCATGCAGAGAATTGACCTCAGCCAGCAACTAACCCTTGCTAGCCTAACAGAAACACTCAAACAAGTTCAAACTAGCC
AAGCTGTCAGAGACAAGATCAATCTTGATAAAATTCTTGCTTTCTTTGACACAGTACTCGGTCAGGAAATTCTTGCTAAT
ACCGACCATCTCTATCGCGAGCAACCTTTCTCCATGCTCAAACGAGACCAAAAGAGTCAGGAAGACTTTGTTGTCCGTGG
TATCCTTGATGGCTATCTGCTTTACGAAAACAAAATTGTTCTGTTCGACTACAAGACAGACCGCTATGATGAACCAAGTC
AACTCGTAGACCGCTATCGTGGTCAGTTAGCTCTATACGAAGAGGCTTTATCACGAGCCTATTCGATTGAAAATATTGAA
AAATACTTGATTTTACTCGGTAAAGACGAGGTTCAAGTTGTAAAAGTATAA

Domains

Predicted by InterProScan.

UvrD-like helicase C-terminal domain (UvrD_C)

(479-896)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1054-1193)

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(29-469)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B1IBR6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

99.095

100

0.991

Multiple sequence alignment