Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexB   Type   Machinery gene
Locus tag   SPH_RS05940 Genome accession   NC_010380
Coordinates   1124783..1128058 (+) Length   1091 a.a.
NCBI ID   WP_000772379.1    Uniprot ID   B1IBR5
Organism   Streptococcus pneumoniae Hungary19A-6     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1119783..1133058
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPH_RS05915 (SPH_1221) - 1119902..1121017 (+) 1116 WP_000706436.1 glycerate kinase -
  SPH_RS05920 (SPH_1220) - 1121014..1121460 (-) 447 WP_000131076.1 YueI family protein -
  SPH_RS05925 (SPH_1222) eno 1121624..1122928 (+) 1305 WP_000022813.1 surface-displayed alpha-enolase -
  SPH_RS12580 (SPH_1223) - 1123066..1123512 (-) 447 WP_001811697.1 tyrosine-type recombinase/integrase -
  SPH_RS12585 - 1123412..1124257 (-) 846 Protein_1142 IS630 family transposase -
  SPH_RS13230 - 1124428..1124583 (+) 156 Protein_1143 diacylglycerol kinase family lipid kinase -
  SPH_RS05940 (SPH_1225) rexB 1124783..1128058 (+) 3276 WP_000772379.1 ATP-dependent nuclease subunit B Machinery gene
  SPH_RS05945 (SPH_1226) rexA 1128055..1131705 (+) 3651 WP_000767219.1 helicase-exonuclease AddAB subunit AddA Machinery gene

Sequence

Protein


Download         Length: 1091 a.a.        Molecular weight: 124818.64 Da        Isoelectric Point: 5.6785

>NTDB_id=27587 SPH_RS05940 WP_000772379.1 1124783..1128058(+) (rexB) [Streptococcus pneumoniae Hungary19A-6]
MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKERAVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTT
LDDIGLGLAFYKCLAELDPKDLRVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVIGAYASKKAYTSPFSEGNLYQAS
VKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLESSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLH
ENSDLSYKHFRILLGDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLLRTDLYTDL
SQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAPLETLFASRKQKAENLLQKWSVFLKEGAVTK
QLQDLTTTLEAVEQERQTEVWKAFCHVLEQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLT
ADFVYAIGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSARKQLFLSAPSLFNESE
SKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSLVAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENP
AIPTSPSSKTLTKDTLQALYPAKQEFYLSTSGLTEFYLNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQLPN
EDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIETIKEEANFGGKDQAFIQLDNGRSV
FVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPHFFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLA
GAVVEASKSMKYQGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYTENGRSIAPYV
QQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREELNR

Nucleotide


Download         Length: 3276 bp        

>NTDB_id=27587 SPH_RS05940 WP_000772379.1 1124783..1128058(+) (rexB) [Streptococcus pneumoniae Hungary19A-6]
ATGAAATTACTTTATACTGATATTCGGACTTCTTTGACAGAAATTCTAACAAGAGAGGCAGAAGAGCTAGTTGCAGCTGG
CAAGCGGGTCTTCTACATTGCCCCCAACTCTCTTTCTTTTGAAAAGGAACGCGCCGTGCTAGAATACTTGTCCCAGCAGG
CTTCTTTTTCGATTACCGTCACGCGCTTTGCTCAAATGGCTCGCTATCTGGTCTTGAATGATTTACCAGCTAAAACTACT
CTTGATGATATCGGTCTTGGGTTGGCCTTTTACAAATGCCTTGCCGAACTCGATCCCAAGGACTTGCGTGTTTATGGCGC
TATTAAGCAGGATCCTCAATTGATCCAGCAGTTAATTGAGCTTTACCATGAGATGACCAAATCTCAGATGAGTTTTTTGG
ACTTGGAGAATTTAACAGATGAGGATAAGAGGGCGGATTTACTCTTGATTTTTGAGAAAGTAACAGCCTATCTTAATCAA
GGTCAGTTAGCCCAGGGAAGTCAGTTGTCCCATTTGATTGAGGCTATTGAGAATGACAAGGTAAGTAGTGATTTTAATCA
AATCGCCTTGGTCATTGACGGCTTTACTCGTTTTTCTGCTGAGGAAGAGCGGGTTGTGGACTTACTTCACGGCAAAGGTG
TTGAGATTGTTATCGGGGCTTATGCTAGTAAGAAAGCCTATACCAGTCCTTTTAGCGAGGGCAATCTCTACCAAGCCAGC
GTAAAATTTCTCCATCATCTGGCTTCTAAATACCAAACGCCTGCTCAGGACTGTTCTCAAACTCATGAGAAGATGGATAG
TTTTGACAAGGCCTCTCGTTTGTTGGAGTCTTCTTATGACTTTTCAGAACTCGCTTTGGATGTCGATGAGAAAGACCGTG
AAAATTTACAAATCTGGTCTTGTTTGACGCAAAAGGAGGAGTTGGAGCTAGTAGCCCGTAGTATTCGTCAGAAATTACAT
GAGAACTCAGACCTGAGCTACAAGCATTTTCGTATTCTCTTGGGGGATGTAGCTTCTTACCAGTTATCTCTCAAAACCAT
TTTTGACCAGTATCAGATTCCTTTTTATCTTGGTAGAAGCGAAGCCATGGCTCATCATCCCTTGACTCAGTTTGTCGAGT
CTATTTTAGCTTTAAAACGTTACCGTTTTCGTCAGGAGGATTTGATCAATCTTCTTAGAACTGATTTGTATACTGACCTC
AGTCAGTCTGATATTGATGCTTTTGAGCAATATATCCGCTATCTTGGTATCAATGGCTTGCCAGCCTTTCAGCAAACCTT
CACCAAATCCCACCATGGAAAATTTAATCTTGAGCGTTTGAATGTCCTCCGCCTGAGAATTTTAGCACCTCTTGAAACCC
TCTTTGCCAGCCGAAAACAAAAGGCTGAAAACCTCCTACAAAAATGGAGTGTCTTTCTAAAAGAAGGAGCTGTGACTAAG
CAGTTACAAGATTTGACAACCACTTTGGAAGCTGTAGAACAGGAAAGACAAACCGAAGTTTGGAAGGCTTTCTGCCATGT
TTTAGAACAATTTGCGACTGTTTTTGCTGGTTCACAGGTTAGTCTGGAAGACTTCCTAGCCTTGCTCCATTCTGGAATGA
GTTTGTCCCAATACCGTACCATTCCAGCAACAGTGGACACTGTTCTGGTGCAGAGTTACGATTTGATTGCACCATTGACT
GCTGACTTTGTCTATGCTATTGGACTAACTCAGGACAATTTACCAAAAATTTCTCAAAACACCAGTCTTCTGACAGATGA
AGAAAGGCAAAACCTAAACCAAACGACCGAAGAAGGCGTTCAATTACTGATTGCCAGCAGTGAAAATCTCAAGAAAAATC
GCTACACTATGCTTTCCTTGGTCAATTCTGCTCGTAAGCAGTTGTTCTTGTCGGCTCCAAGCCTTTTTAACGAAAGTGAA
AGTAAGGAATCTGCCTATCTTCAAGAGTTGATCCATTTTGGATTTAGGCGGAGAGAGAAGAGGATGAATCACAAAGGACT
GTCTAAGGAGGATATGGGGTCCTATCACAGTCTTTTGTCTAGTCTGGTTGCCTATCACCAGCAGGGTGAGATGAGCGATA
CTGAGCAAGATTTGACTTTTGTCAAGGTTCTGTCGCGTGTCATAGGTAAAAAACTAGATCTGCAAGGTCTGGAAAATCCA
GCTATCCCAACCAGTCCAAGCAGCAAGACCTTAACCAAGGACACCTTGCAAGCTCTCTATCCTGCCAAACAGGAGTTTTA
CCTGTCTACGTCGGGTTTGACAGAGTTCTATCTCAATGAATACAGTTATTTCCTACGCTACGTTTTAGGCTTGCAGGAGG
AATTACGTTTGCGTCCTGATGCCCGTAGTCACGGGAATTTCTTGCATCGTATCTTTGAACGCGCCTTACAGTTGCCTAAT
GAAGATTCCTTTGACCAACGTCTAGAACAAGCTATTCAAGAAACCAGTCAAGAACGCGAATTTGAAGCTATTTATCAAGA
AAGTTTGGAAGCCCAGTTTACCAAGGAAGTTTTGCTTGATGTTGCACGGACGACTGGACATATTCTCCGACACAATCCAG
CCATCGAAACCATCAAAGAAGAAGCAAATTTTGGTGGAAAAGACCAAGCCTTTATTCAATTAGACAATGGACGCAGTGTC
TTTGTACGAGGCAAGGTGGACCGGATTGACCGTTTGAAAGCTAATGGAGCGATAGGAGTAGTAGACTACAAATCCAGTCT
GACTCAGTTCCAGTTTCCTCATTTCTTTAATGGGCTCAATTCTCAGTTACCAACCTATCTTGCTGCCCTAAAAAGAGAAG
GGGAGCAGAACTTTTTCGGCGCCATGTACTTGGAAATGGCTGAACCTGTCCAATCTCTGATGGCGGTAAAAAGTCTGGCA
GGAGCAGTGGTAGAAGCCAGCAAATCTATGAAATACCAAGGGCTCTTCTTGGAAAAAGAAAGCAGTTATTTAGGCGAATT
TTATAACAAAAACAAGGCTAATCAACTGACAGATGAGGAATTTCAGCTCCTACTGGACTACAATGCCTATCTTTACAAGA
AAGCTGCTGAGAAGATTTTAGCAGGCCGGTTCGCCATCAATCCTTATACTGAAAATGGCAGAAGCATTGCCCCATACGTC
CAGCAACATCAGGCTATTACAGGCTTTGAAGCCAATTACCATCTGGGCCAAGCCCGTTTCCTAGAAAAGTTGGACCTAGC
TGATGGCAAGCGTCTGGTCGGAGAAAAACTCAAGCAAGCTTGGCTTGAAAAAATAAGAGAGGAGTTGAATCGATGA

Domains

Predicted by InterProScan.

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(748-1030)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B1IBR5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexB Streptococcus pneumoniae R6

99.267

100

0.993

Multiple sequence alignment