Detailed information
Bioinformatically predicted
Overview
| Name | comFA | Type | Machinery gene |
| Locus tag | C5Z25_RS09230 | Genome accession | NZ_CP027190 |
| Coordinates | 1919924..1921276 (+) | Length | 450 a.a. |
| NCBI ID | WP_105452351.1 | Uniprot ID | A0A2R3JQQ8 |
| Organism | Lactobacillus sp. CBA3605 | ||
| Function | ssDNA transport into the cell (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1881357..1919856 | 1919924..1921276 | flank | 68 |
Gene organization within MGE regions
Location: 1881357..1921276
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C5Z25_RS09030 (C5Z25_09030) | - | 1881357..1882340 (-) | 984 | WP_105452319.1 | DNA/RNA non-specific endonuclease | - |
| C5Z25_RS09035 (C5Z25_09035) | - | 1882360..1883004 (-) | 645 | WP_105452320.1 | cell surface protein | - |
| C5Z25_RS09040 (C5Z25_09040) | mprF | 1883292..1885913 (+) | 2622 | WP_105452321.1 | bifunctional lysylphosphatidylglycerol flippase/synthetase MprF | - |
| C5Z25_RS09045 (C5Z25_09045) | - | 1886009..1886584 (-) | 576 | WP_105452322.1 | TIGR00730 family Rossman fold protein | - |
| C5Z25_RS09050 (C5Z25_09050) | nrdF | 1886677..1887693 (-) | 1017 | WP_105449862.1 | class 1b ribonucleoside-diphosphate reductase subunit beta | - |
| C5Z25_RS09055 (C5Z25_09055) | nrdE | 1887723..1889888 (-) | 2166 | WP_105452323.1 | class 1b ribonucleoside-diphosphate reductase subunit alpha | - |
| C5Z25_RS09060 (C5Z25_09060) | - | 1890024..1890254 (-) | 231 | WP_105452324.1 | redoxin NrdH | - |
| C5Z25_RS09065 (C5Z25_09065) | - | 1890477..1891097 (+) | 621 | WP_105452325.1 | class I SAM-dependent methyltransferase | - |
| C5Z25_RS09070 (C5Z25_09070) | - | 1891114..1891593 (+) | 480 | WP_105452877.1 | nucleoside deaminase | - |
| C5Z25_RS09080 (C5Z25_09080) | dnaX | 1891834..1893531 (+) | 1698 | WP_105452326.1 | DNA polymerase III subunit gamma/tau | - |
| C5Z25_RS09085 (C5Z25_09085) | - | 1893555..1893863 (+) | 309 | WP_105452327.1 | YbaB/EbfC family nucleoid-associated protein | - |
| C5Z25_RS09090 (C5Z25_09090) | recR | 1893890..1894489 (+) | 600 | WP_105449868.1 | recombination mediator RecR | - |
| C5Z25_RS09095 (C5Z25_09095) | - | 1894505..1894756 (+) | 252 | WP_105450177.1 | YaaL family protein | - |
| C5Z25_RS09100 (C5Z25_09100) | tmk | 1894947..1895612 (+) | 666 | WP_105450178.1 | dTMP kinase | - |
| C5Z25_RS09105 (C5Z25_09105) | - | 1895609..1895938 (+) | 330 | WP_105452328.1 | cyclic-di-AMP receptor | - |
| C5Z25_RS09110 (C5Z25_09110) | holB | 1895957..1896982 (+) | 1026 | WP_105452329.1 | DNA polymerase III subunit delta' | - |
| C5Z25_RS09115 (C5Z25_09115) | - | 1897003..1897350 (+) | 348 | WP_105449871.1 | DNA replication initiation control protein YabA | - |
| C5Z25_RS09120 (C5Z25_09120) | rsmI | 1897373..1898251 (+) | 879 | WP_105452330.1 | 16S rRNA (cytidine(1402)-2'-O)-methyltransferase | - |
| C5Z25_RS09125 (C5Z25_09125) | - | 1898267..1899052 (+) | 786 | WP_105452331.1 | acyl-[acyl-carrier-protein] thioesterase | - |
| C5Z25_RS09130 (C5Z25_09130) | galE | 1899176..1900171 (+) | 996 | WP_105452332.1 | UDP-glucose 4-epimerase GalE | - |
| C5Z25_RS09135 (C5Z25_09135) | phnW | 1900268..1901368 (-) | 1101 | WP_105452333.1 | 2-aminoethylphosphonate--pyruvate transaminase | - |
| C5Z25_RS09140 (C5Z25_09140) | phnX | 1901388..1902185 (-) | 798 | WP_105452334.1 | phosphonoacetaldehyde hydrolase | - |
| C5Z25_RS09145 (C5Z25_09145) | - | 1902211..1903065 (-) | 855 | WP_105452335.1 | ABC transporter permease | - |
| C5Z25_RS09150 (C5Z25_09150) | phnE | 1903062..1903865 (-) | 804 | WP_105452336.1 | phosphonate ABC transporter, permease protein PhnE | - |
| C5Z25_RS09155 (C5Z25_09155) | phnC | 1903855..1904628 (-) | 774 | WP_105452337.1 | phosphonate ABC transporter ATP-binding protein | - |
| C5Z25_RS09160 (C5Z25_09160) | - | 1904668..1905714 (-) | 1047 | WP_105452338.1 | phosphate/phosphite/phosphonate ABC transporter substrate-binding protein | - |
| C5Z25_RS09165 (C5Z25_09165) | tsaB | 1906011..1906736 (+) | 726 | WP_105452339.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB | - |
| C5Z25_RS09170 (C5Z25_09170) | rimI | 1906720..1907301 (+) | 582 | WP_105452340.1 | ribosomal protein S18-alanine N-acetyltransferase | - |
| C5Z25_RS09175 (C5Z25_09175) | rimI | 1907294..1907755 (+) | 462 | WP_105452341.1 | ribosomal protein S18-alanine N-acetyltransferase | - |
| C5Z25_RS09180 (C5Z25_09180) | tsaD | 1907768..1908805 (+) | 1038 | WP_105452342.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD | - |
| C5Z25_RS09185 (C5Z25_09185) | - | 1908913..1910895 (-) | 1983 | WP_105452343.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| C5Z25_RS09190 (C5Z25_09190) | - | 1911062..1911718 (+) | 657 | WP_105449886.1 | redox-sensing transcriptional repressor Rex | - |
| C5Z25_RS09195 (C5Z25_09195) | - | 1911771..1912406 (-) | 636 | WP_105452344.1 | CPBP family intramembrane glutamic endopeptidase | - |
| C5Z25_RS09200 (C5Z25_09200) | groES | 1912597..1912881 (+) | 285 | WP_105452345.1 | co-chaperone GroES | - |
| C5Z25_RS09205 (C5Z25_09205) | groL | 1912937..1914562 (+) | 1626 | WP_105452346.1 | chaperonin GroEL | - |
| C5Z25_RS09210 (C5Z25_09210) | - | 1914788..1916623 (+) | 1836 | WP_105452347.1 | APC family permease | - |
| C5Z25_RS09215 (C5Z25_09215) | - | 1916786..1917883 (+) | 1098 | WP_105452348.1 | glycosyltransferase family 4 protein | - |
| C5Z25_RS09220 (C5Z25_09220) | - | 1918197..1919096 (+) | 900 | WP_105452349.1 | phosphate ABC transporter substrate-binding protein | - |
| C5Z25_RS09225 (C5Z25_09225) | - | 1919215..1919856 (-) | 642 | WP_105452350.1 | YigZ family protein | - |
| C5Z25_RS09230 (C5Z25_09230) | comFA | 1919924..1921276 (+) | 1353 | WP_105452351.1 | DEAD/DEAH box helicase | Machinery gene |
Sequence
Protein
Download Length: 450 a.a. Molecular weight: 50847.07 Da Isoelectric Point: 10.5038
>NTDB_id=275657 C5Z25_RS09230 WP_105452351.1 1919924..1921276(+) (comFA) [Lactobacillus sp. CBA3605]
MQVNELYGRQLNLTVAQASDLPVNTQRFASMQVTTSLVQCQRCHSRLKRAWAQLPNQQYYCYQCLNLGRISTLTSLYHIP
EPNDFPKRPKLTWTGTLTPQQTACAATIQDKFATHQHHLLWAVTGAGKTEMLFPGLAWALAQGLRVAVASPRVDVCLELY
PRLQAAFAGLDIALLHGRQTEPYRYCQLTVCTTHQLLRFRAAFDVLIIDEVDAFPFAANPRLTYAVTQALKTTGALLYLT
ATPSRALLCQVRQHQLSISYLPLRFHQHLLPVIKVTLRPNWWRQIKHGQLPTLLRHWLQEYAHTQRRFLLFVPRVSQLTL
VQAAVQQNIPELTGLTVHSTDPDRLAKVQKMRSATVQYLITTTILERGVTFPGIDVIVLGADDTIFSTAALVQIAGRVGR
SKERPTGLVRFICSSYARPVKQAQRQIKQVNRKGRRLLNELSTVSTTVTT
MQVNELYGRQLNLTVAQASDLPVNTQRFASMQVTTSLVQCQRCHSRLKRAWAQLPNQQYYCYQCLNLGRISTLTSLYHIP
EPNDFPKRPKLTWTGTLTPQQTACAATIQDKFATHQHHLLWAVTGAGKTEMLFPGLAWALAQGLRVAVASPRVDVCLELY
PRLQAAFAGLDIALLHGRQTEPYRYCQLTVCTTHQLLRFRAAFDVLIIDEVDAFPFAANPRLTYAVTQALKTTGALLYLT
ATPSRALLCQVRQHQLSISYLPLRFHQHLLPVIKVTLRPNWWRQIKHGQLPTLLRHWLQEYAHTQRRFLLFVPRVSQLTL
VQAAVQQNIPELTGLTVHSTDPDRLAKVQKMRSATVQYLITTTILERGVTFPGIDVIVLGADDTIFSTAALVQIAGRVGR
SKERPTGLVRFICSSYARPVKQAQRQIKQVNRKGRRLLNELSTVSTTVTT
Nucleotide
Download Length: 1353 bp
>NTDB_id=275657 C5Z25_RS09230 WP_105452351.1 1919924..1921276(+) (comFA) [Lactobacillus sp. CBA3605]
ATGCAAGTGAATGAGTTATATGGTCGCCAGCTTAATCTAACAGTCGCTCAGGCTAGCGACTTACCAGTTAATACGCAACG
TTTTGCGAGTATGCAAGTGACCACTAGTTTAGTGCAATGTCAACGTTGTCATAGTCGGTTAAAGCGTGCATGGGCACAAT
TACCCAATCAACAGTATTACTGCTATCAGTGTTTGAATCTGGGCCGGATTAGCACCCTAACTTCACTGTATCATATTCCG
GAACCTAATGACTTTCCTAAGCGGCCTAAATTAACTTGGACTGGTACGTTAACCCCACAACAAACCGCTTGTGCAGCAAC
TATTCAGGATAAGTTTGCGACACATCAACACCACTTACTTTGGGCAGTTACGGGCGCCGGCAAGACCGAGATGTTGTTTC
CGGGGTTAGCTTGGGCATTGGCACAAGGCTTGCGAGTTGCAGTGGCTTCACCACGGGTTGATGTTTGCTTAGAACTATAC
CCGCGGTTACAGGCAGCTTTTGCTGGCTTGGATATTGCCTTACTACATGGGCGACAAACCGAGCCTTATCGTTATTGTCA
ACTGACCGTTTGTACTACACATCAATTGTTGCGATTTCGAGCGGCTTTCGATGTGTTAATTATTGATGAAGTAGATGCGT
TTCCATTTGCTGCTAATCCACGTTTGACTTATGCCGTGACGCAAGCCTTAAAAACAACGGGGGCATTATTATATTTGACA
GCCACGCCTAGTCGAGCGTTGCTGTGCCAAGTACGACAGCATCAGTTAAGTATCAGCTATTTGCCATTACGATTTCATCA
GCATTTATTACCGGTCATTAAGGTAACCCTACGGCCCAATTGGTGGCGTCAAATTAAACACGGCCAGTTACCAACCTTGT
TACGACACTGGTTACAGGAATATGCGCATACGCAGCGTCGATTTTTATTGTTTGTGCCCCGAGTCAGTCAACTGACATTG
GTTCAGGCGGCCGTGCAACAAAATATTCCGGAATTAACCGGTTTAACAGTGCATTCAACTGATCCTGACCGGTTGGCGAA
AGTTCAGAAGATGCGTTCGGCGACAGTACAATATTTAATTACGACGACGATTTTAGAACGTGGCGTGACGTTTCCTGGTA
TTGATGTGATTGTGTTAGGTGCTGATGATACCATTTTTTCAACGGCAGCGTTAGTTCAGATTGCAGGGCGCGTAGGTCGT
TCAAAAGAGCGGCCCACTGGCTTAGTGCGTTTTATTTGTAGCAGTTACGCACGGCCAGTCAAACAAGCCCAACGCCAAAT
TAAGCAAGTTAATCGGAAAGGTCGGCGCTTACTAAATGAACTGTCTACTGTGTCAACGACCGTTACAACCTGA
ATGCAAGTGAATGAGTTATATGGTCGCCAGCTTAATCTAACAGTCGCTCAGGCTAGCGACTTACCAGTTAATACGCAACG
TTTTGCGAGTATGCAAGTGACCACTAGTTTAGTGCAATGTCAACGTTGTCATAGTCGGTTAAAGCGTGCATGGGCACAAT
TACCCAATCAACAGTATTACTGCTATCAGTGTTTGAATCTGGGCCGGATTAGCACCCTAACTTCACTGTATCATATTCCG
GAACCTAATGACTTTCCTAAGCGGCCTAAATTAACTTGGACTGGTACGTTAACCCCACAACAAACCGCTTGTGCAGCAAC
TATTCAGGATAAGTTTGCGACACATCAACACCACTTACTTTGGGCAGTTACGGGCGCCGGCAAGACCGAGATGTTGTTTC
CGGGGTTAGCTTGGGCATTGGCACAAGGCTTGCGAGTTGCAGTGGCTTCACCACGGGTTGATGTTTGCTTAGAACTATAC
CCGCGGTTACAGGCAGCTTTTGCTGGCTTGGATATTGCCTTACTACATGGGCGACAAACCGAGCCTTATCGTTATTGTCA
ACTGACCGTTTGTACTACACATCAATTGTTGCGATTTCGAGCGGCTTTCGATGTGTTAATTATTGATGAAGTAGATGCGT
TTCCATTTGCTGCTAATCCACGTTTGACTTATGCCGTGACGCAAGCCTTAAAAACAACGGGGGCATTATTATATTTGACA
GCCACGCCTAGTCGAGCGTTGCTGTGCCAAGTACGACAGCATCAGTTAAGTATCAGCTATTTGCCATTACGATTTCATCA
GCATTTATTACCGGTCATTAAGGTAACCCTACGGCCCAATTGGTGGCGTCAAATTAAACACGGCCAGTTACCAACCTTGT
TACGACACTGGTTACAGGAATATGCGCATACGCAGCGTCGATTTTTATTGTTTGTGCCCCGAGTCAGTCAACTGACATTG
GTTCAGGCGGCCGTGCAACAAAATATTCCGGAATTAACCGGTTTAACAGTGCATTCAACTGATCCTGACCGGTTGGCGAA
AGTTCAGAAGATGCGTTCGGCGACAGTACAATATTTAATTACGACGACGATTTTAGAACGTGGCGTGACGTTTCCTGGTA
TTGATGTGATTGTGTTAGGTGCTGATGATACCATTTTTTCAACGGCAGCGTTAGTTCAGATTGCAGGGCGCGTAGGTCGT
TCAAAAGAGCGGCCCACTGGCTTAGTGCGTTTTATTTGTAGCAGTTACGCACGGCCAGTCAAACAAGCCCAACGCCAAAT
TAAGCAAGTTAATCGGAAAGGTCGGCGCTTACTAAATGAACTGTCTACTGTGTCAACGACCGTTACAACCTGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comFA | Latilactobacillus sakei subsp. sakei 23K |
49.543 |
97.333 |
0.482 |
| comFA/cflA | Streptococcus mitis NCTC 12261 |
40.678 |
91.778 |
0.373 |
| comFA | Bacillus subtilis subsp. subtilis str. 168 |
40.64 |
90.222 |
0.367 |
| comFA/cflA | Streptococcus pneumoniae TIGR4 |
39.609 |
90.889 |
0.36 |
| comFA/cflA | Streptococcus pneumoniae D39 |
39.609 |
90.889 |
0.36 |
| comFA/cflA | Streptococcus pneumoniae Rx1 |
39.609 |
90.889 |
0.36 |
| comFA/cflA | Streptococcus pneumoniae R6 |
39.609 |
90.889 |
0.36 |
| comFA | Lactococcus lactis subsp. cremoris KW2 |
39.706 |
90.667 |
0.36 |