Detailed information NTG0027524

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: SSA_RS05390
• Genome accession: NC_009009
• Coordinates: 1110476..1111705 (+)
• Length: 409 a.a.
• NCBI ID: WP_002895582.1
• Uniprot ID: A0A3R9G2C7
• Organism: Streptococcus sanguinis SK36
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1105476..1116705

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSA_RS05365	-	1106529..1107116 (+)	588	WP_002900433.1	hypothetical protein	-
SSA_RS05370 (SSA_1088)	-	1107188..1107598 (+)	411	WP_011836913.1	GNAT family N-acetyltransferase	-
SSA_RS05375 (SSA_1090)	-	1107711..1108670 (+)	960	WP_009660448.1	ROK family glucokinase	-
SSA_RS05380 (SSA_1091)	-	1108775..1109614 (+)	840	WP_002902863.1	thymidylate synthase	-
SSA_RS05385 (SSA_1092)	-	1109739..1110251 (+)	513	WP_002902864.1	dihydrofolate reductase	-
SSA_RS05390 (SSA_1093)	clpX	1110476..1111705 (+)	1230	WP_002895582.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
SSA_RS05395 (SSA_1094)	yihA	1111716..1112303 (+)	588	WP_002915299.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
SSA_RS05400 (SSA_1095)	-	1112450..1113148 (+)	699	WP_011836915.1	glucosaminidase domain-containing protein	-
SSA_RS05405 (SSA_1096)	mmuM	1113212..1114159 (+)	948	WP_011836916.1	homocysteine S-methyltransferase	-
SSA_RS05410 (SSA_1098)	-	1114274..1115071 (+)	798	WP_011836917.1	formate/nitrite transporter family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45617.05 Da
• Isoelectric Point: 4.3984

>NTDB_id=27524 SSA_RS05390 WP_002895582.1 1110476..1111705(+) (clpX) [Streptococcus sanguinis SK36]
MPTSRNDDMMVFCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINYHDSREEEDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNRAIDEDSSYMQEIISEDVQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LKEPRNALIKQYQALLSYDDVKLEFDEDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVDG
TDKPILETA

Nucleotide

• Length: 1230 bp

>NTDB_id=27524 SSA_RS05390 WP_002895582.1 1110476..1111705(+) (clpX) [Streptococcus sanguinis SK36]
ATGCCTACAAGTCGTAATGATGATATGATGGTTTTTTGTTCTTTCTGTGGGAAGAACCAAGATGAGGTTCAGAAGATTAT
TGCTGGAAATAATGCCTTCATCTGTAATGAATGTGTGGAACTGGCGCAGGAAATCATCCGTGAAGAGTTAGCCGAGGAAG
TGCTGGCAGATCTGTCTGAGGTACCAAAACCTCAGGAGCTGCTGAACATCTTGAACCACTATGTTATCGGGCAAGACCGA
GCAAAGCGTGCCTTAGCAGTAGCGGTCTATAATCACTACAAGCGTATTAACTACCACGACAGCCGTGAAGAAGAAGATGT
GGAACTGCAAAAGTCAAATATTTTGATGATCGGCCCGACTGGGTCGGGTAAGACCTTTCTGGCGCAGACTCTGGCTCGCA
GCCTCAATGTGCCTTTCGCCATTGCGGACGCAACTGCTCTGACTGAAGCTGGTTATGTCGGAGAAGATGTGGAAAATATC
CTCCTCAAGCTTTTGCAGGCGGCTGACTTTAATATTGAGCGCGCAGAACGCGGCATTATCTATGTCGATGAGATTGACAA
GATCGCTAAAAAAGGCGAAAACGTCTCGATCACCCGTGATGTTTCGGGTGAAGGAGTTCAGCAAGCTCTGCTGAAGATTA
TCGAAGGAACAGTAGCTAGTGTACCGCCGCAAGGTGGACGCAAGCATCCGCAGCAGGAAATGATTCAAGTTGATACTAAG
AACATTCTCTTCATCGTTGGCGGTGCTTTTGACGGTATCGAAGAAATCGTAAAACAGCGTCTGGGTGAGAAAATCATTGG
TTTCGGTCAGAACAACCGAGCAATCGACGAAGATAGTTCCTACATGCAGGAAATTATCTCAGAAGACGTTCAAAAGTTTG
GGATTATTCCTGAGTTGATTGGCCGTTTGCCTGTTTTTGCTGCTCTGGAGCAGCTGACAGTTGATGATTTGGTCCGGATT
CTGAAAGAGCCTAGAAACGCCCTTATTAAGCAGTATCAGGCACTTCTATCTTATGATGATGTTAAACTTGAATTTGACGA
GGATGCTCTGCAGGAGATCGCAAATAAAGCGATTGAACGTAAAACAGGTGCACGAGGGCTTCGCTCTATCATTGAAGAAA
CTATGATGGATGTCATGTTTGAAGTTCCAAGTCAGGAAAATGTCAAACTTGTCCGTATTACCAAAGAAGCAGTAGATGGA
ACAGATAAGCCTATTCTAGAAACTGCCTAA

Domains

Predicted by InterproScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-389)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

3D structure

• AlphaFold DB: A0A3R9G2C7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	85.819	100	0.858
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.606	98.044	0.565