Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AM340_RS23165 Genome accession   NZ_CP032204
Coordinates   4501783..4502439 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain AR_0013     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4496783..4507439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AM340_RS23125 (AM340_23430) - 4497294..4497554 (+) 261 WP_000488112.1 ogr/Delta-like zinc finger family protein -
  AM340_RS23130 (AM340_23435) - 4497746..4497886 (+) 141 WP_000078920.1 Hok/Gef family protein -
  AM340_RS28680 - 4498075..4498356 (-) 282 WP_001303543.1 hypothetical protein -
  AM340_RS23155 (AM340_23460) pgsA 4499349..4499897 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AM340_RS23160 (AM340_23465) uvrC 4499954..4501786 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AM340_RS23165 (AM340_23470) letA 4501783..4502439 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AM340_RS28685 yecU 4502735..4502911 (+) 177 WP_032142748.1 protein YecU -
  AM340_RS23170 (AM340_23475) yecF 4502898..4503122 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  AM340_RS23175 (AM340_23480) sdiA 4503190..4503912 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  AM340_RS23180 (AM340_23485) tcyN 4504142..4504894 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AM340_RS23185 (AM340_23490) tcyL 4504891..4505559 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  AM340_RS23190 (AM340_23495) dcyD 4505574..4506560 (-) 987 WP_001128202.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=275058 AM340_RS23165 WP_000611328.1 4501783..4502439(-) (letA) [Escherichia coli strain AR_0013]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=275058 AM340_RS23165 WP_000611328.1 4501783..4502439(-) (letA) [Escherichia coli strain AR_0013]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTTGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment