Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D3F09_RS10420 Genome accession   NZ_CP032145
Coordinates   2141472..2142128 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 15.TR.026_OXA     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2136472..2147128
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D3F09_RS10390 (D3F09_10970) yecA 2137723..2138388 (-) 666 WP_000847880.1 UPF0149 family protein YecA -
  D3F09_RS10410 (D3F09_10990) pgsA 2139038..2139586 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  D3F09_RS10415 (D3F09_10995) uvrC 2139643..2141475 (-) 1833 WP_060579134.1 excinuclease ABC subunit UvrC Machinery gene
  D3F09_RS10420 (D3F09_11000) letA 2141472..2142128 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  D3F09_RS26715 (D3F09_11005) - 2142270..2142386 (+) 117 WP_023063716.1 hypothetical protein -
  D3F09_RS10430 yecU 2142424..2142600 (+) 177 WP_000590344.1 protein YecU -
  D3F09_RS10435 (D3F09_11010) yecF 2142587..2142811 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  D3F09_RS10440 (D3F09_11015) sdiA 2142878..2143600 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  D3F09_RS10445 (D3F09_11020) tcyN 2143830..2144582 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  D3F09_RS10450 (D3F09_11025) tcyL 2144579..2145247 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  D3F09_RS10455 (D3F09_11030) dcyD 2145262..2146248 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=274691 D3F09_RS10420 WP_000611328.1 2141472..2142128(-) (letA) [Escherichia coli strain 15.TR.026_OXA]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=274691 D3F09_RS10420 WP_000611328.1 2141472..2142128(-) (letA) [Escherichia coli strain 15.TR.026_OXA]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGTGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482