Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D3C65_RS12520 Genome accession   NZ_CP032126
Coordinates   2589389..2590033 (+) Length   214 a.a.
NCBI ID   WP_003090351.1    Uniprot ID   A0A0H2ZC55
Organism   Pseudomonas aeruginosa strain PAO1161     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2584389..2595033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D3C65_RS12500 (D3C65_12485) - 2585024..2586238 (+) 1215 WP_003113355.1 MFS transporter -
  D3C65_RS12505 (D3C65_12490) - 2586254..2587282 (-) 1029 WP_003097554.1 AraC family transcriptional regulator -
  D3C65_RS12510 (D3C65_12495) pqsH 2587900..2589048 (+) 1149 WP_003090354.1 2-heptyl-3-hydroxy-4(1H)-quinolone synthase -
  D3C65_RS12520 (D3C65_12505) letA 2589389..2590033 (+) 645 WP_003090351.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  D3C65_RS12525 (D3C65_12510) uvrC 2590034..2591860 (+) 1827 WP_003113354.1 excinuclease ABC subunit UvrC -
  D3C65_RS12530 (D3C65_12515) pgsA 2591894..2592454 (+) 561 WP_003090349.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23608.53 Da        Isoelectric Point: 6.1073

>NTDB_id=274608 D3C65_RS12520 WP_003090351.1 2589389..2590033(+) (letA) [Pseudomonas aeruginosa strain PAO1161]
MIKVLVVDDHDLVRTGITRMLADIEGLQVVGQADCGEDCLKLARELKPDVVLMDVKMPGIGGLEATRKLLRSQPDIKVVV
VTVCEEDPFPTRLMQAGAAGYMTKGAGLEEMVQAIRQVFAGQRYISPQIAQQLALKSFQPQQHDSPFDSLSEREIQIALM
IANCHKVQSISDKLCLSPKTVNTYRYRIFEKLSITSDVELALLAVRHGMVDAAS

Nucleotide


Download         Length: 645 bp        

>NTDB_id=274608 D3C65_RS12520 WP_003090351.1 2589389..2590033(+) (letA) [Pseudomonas aeruginosa strain PAO1161]
GTGATTAAGGTGCTGGTGGTCGACGACCACGATCTGGTACGCACCGGTATTACCCGCATGCTGGCCGACATCGAAGGCTT
GCAAGTGGTCGGCCAGGCCGACTGCGGTGAAGACTGTCTGAAACTGGCCCGCGAACTGAAGCCGGATGTCGTCCTGATGG
ACGTGAAGATGCCCGGTATCGGCGGCCTGGAGGCGACCCGCAAGCTGCTGCGCAGCCAGCCCGACATCAAGGTCGTGGTA
GTCACCGTCTGCGAAGAGGATCCGTTCCCCACCCGCCTCATGCAGGCCGGCGCCGCCGGCTACATGACCAAGGGCGCGGG
GCTGGAGGAAATGGTCCAGGCGATTCGCCAGGTCTTCGCCGGCCAGCGCTATATCAGCCCGCAGATCGCCCAGCAACTGG
CGCTGAAGTCCTTCCAGCCGCAGCAGCACGATTCCCCCTTCGATTCGCTGTCCGAGCGCGAGATCCAGATCGCCCTGATG
ATCGCCAACTGCCACAAGGTGCAGAGCATCTCCGACAAGCTGTGCCTGTCGCCGAAGACCGTGAATACCTATCGCTACCG
CATCTTCGAGAAGCTCTCGATCACCAGCGACGTGGAACTGGCGCTGCTCGCCGTCCGCCACGGCATGGTCGATGCCGCCA
GCTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZC55

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

54.502

98.598

0.537
  letA Legionella pneumophila strain ERS1305867

54.502

98.598

0.537