Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D2194_RS08780 Genome accession   NZ_CP032073
Coordinates   1844948..1845604 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CT29     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1839948..1850604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2194_RS08750 (D2194_09470) dcyD 1840827..1841813 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  D2194_RS08755 (D2194_09475) tcyL 1841828..1842496 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  D2194_RS08760 (D2194_09480) tcyN 1842493..1843245 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  D2194_RS08765 (D2194_09485) sdiA 1843475..1844197 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  D2194_RS08770 (D2194_09490) yecF 1844265..1844489 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  D2194_RS08775 yecU 1844476..1844652 (-) 177 WP_000590344.1 protein YecU -
  D2194_RS23975 (D2194_09495) - 1844690..1844806 (-) 117 WP_001302039.1 hypothetical protein -
  D2194_RS08780 (D2194_09500) letA 1844948..1845604 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  D2194_RS08785 (D2194_09505) uvrC 1845601..1847433 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  D2194_RS08790 (D2194_09510) pgsA 1847490..1848038 (+) 549 WP_032278420.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  D2194_RS08810 (D2194_09530) yecA 1848688..1849353 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=274357 D2194_RS08780 WP_000611328.1 1844948..1845604(+) (letA) [Escherichia coli strain CT29]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=274357 D2194_RS08780 WP_000611328.1 1844948..1845604(+) (letA) [Escherichia coli strain CT29]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482