Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D2J89_RS17795 Genome accession   NZ_CP032066
Coordinates   3745218..3745874 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain E166     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3740218..3750874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2J89_RS17765 (D2J89_19190) dcyD 3741098..3742084 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  D2J89_RS17770 (D2J89_19195) tcyL 3742099..3742767 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  D2J89_RS17775 (D2J89_19200) tcyN 3742764..3743516 (+) 753 WP_001272987.1 L-cystine ABC transporter ATP-binding protein TcyN -
  D2J89_RS17780 (D2J89_19205) sdiA 3743746..3744468 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  D2J89_RS17785 (D2J89_19210) yecF 3744535..3744759 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  D2J89_RS17790 yecU 3744746..3744922 (-) 177 WP_000590347.1 protein YecU -
  D2J89_RS26215 - 3745005..3745076 (-) 72 Protein_3501 transcriptional regulator -
  D2J89_RS17795 (D2J89_19215) letA 3745218..3745874 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  D2J89_RS17800 (D2J89_19220) uvrC 3745871..3747703 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  D2J89_RS17805 (D2J89_19225) pgsA 3747760..3748308 (+) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  D2J89_RS17825 (D2J89_19245) yecA 3748957..3749622 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=274308 D2J89_RS17795 WP_000611335.1 3745218..3745874(+) (letA) [Escherichia coli strain E166]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=274308 D2J89_RS17795 WP_000611335.1 3745218..3745874(+) (letA) [Escherichia coli strain E166]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment