Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   D2E16_RS02370 Genome accession   NZ_CP032064
Coordinates   482993..483634 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain YSJ17     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 477993..488634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2E16_RS12615 - 479097..479312 (+) 216 Protein_426 serine/threonine protein kinase -
  D2E16_RS02355 (D2E16_02440) - 479647..480519 (+) 873 WP_414930149.1 IS110 family transposase -
  D2E16_RS12620 - 480544..480768 (+) 225 WP_002940161.1 hypothetical protein -
  D2E16_RS02360 (D2E16_02445) liaF 481349..482008 (+) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  D2E16_RS02365 (D2E16_02450) - 482005..483021 (+) 1017 WP_002937028.1 sensor histidine kinase -
  D2E16_RS02370 (D2E16_02455) vraR 482993..483634 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  D2E16_RS02375 (D2E16_02460) - 483684..485084 (+) 1401 WP_029186185.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  D2E16_RS02380 (D2E16_02465) - 485086..485457 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  D2E16_RS02385 (D2E16_02470) cysK 485483..486409 (-) 927 WP_044687885.1 cysteine synthase A -
  D2E16_RS02390 (D2E16_02475) - 486499..487131 (-) 633 WP_192370181.1 YigZ family protein -
  D2E16_RS02395 (D2E16_02480) comFA/cflA 487188..488480 (+) 1293 WP_192370179.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=274164 D2E16_RS02370 WP_002937025.1 482993..483634(+) (vraR) [Streptococcus suis strain YSJ17]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=274164 D2E16_RS02370 WP_002937025.1 482993..483634(+) (vraR) [Streptococcus suis strain YSJ17]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTCCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCTTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413