Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   D2E16_RS00365 Genome accession   NZ_CP032064
Coordinates   71706..73643 (+) Length   645 a.a.
NCBI ID   WP_192369290.1    Uniprot ID   -
Organism   Streptococcus suis strain YSJ17     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 66706..78643
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2E16_RS00345 (D2E16_00360) tnpA 66833..67327 (+) 495 Protein_49 IS200/IS605 family transposase -
  D2E16_RS00350 (D2E16_00365) comR 67537..68436 (+) 900 WP_024377696.1 helix-turn-helix domain-containing protein Regulator
  D2E16_RS00355 (D2E16_00370) - 68654..69874 (+) 1221 WP_105129612.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  D2E16_RS00360 (D2E16_00380) - 70065..71588 (+) 1524 WP_105127847.1 quinol oxidase -
  D2E16_RS00365 (D2E16_00385) hexB 71706..73643 (+) 1938 WP_192369290.1 DNA mismatch repair endonuclease MutL Machinery gene
  D2E16_RS00370 (D2E16_00390) ruvA 73682..74272 (+) 591 WP_136648117.1 Holliday junction branch migration protein RuvA Machinery gene
  D2E16_RS00375 (D2E16_00395) - 74546..75115 (+) 570 WP_192369291.1 DNA-3-methyladenine glycosylase I -
  D2E16_RS00380 (D2E16_00400) cinA 75152..76333 (+) 1182 WP_192369292.1 competence/damage-inducible protein A Machinery gene
  D2E16_RS00385 (D2E16_00405) recA 76385..77536 (+) 1152 WP_192369293.1 recombinase RecA Machinery gene
  D2E16_RS00390 (D2E16_00410) spx 77695..78093 (+) 399 WP_105108276.1 transcriptional regulator Spx -
  D2E16_RS00395 (D2E16_00415) - 78199..78465 (+) 267 WP_105108277.1 IreB family regulatory phosphoprotein -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72875.05 Da        Isoelectric Point: 5.1693

>NTDB_id=274137 D2E16_RS00365 WP_192369290.1 71706..73643(+) (hexB) [Streptococcus suis strain YSJ17]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKNQSDLFRIRTLGFRGEALPSIASVSHIVIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFVLVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIRQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIGSGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=274137 D2E16_RS00365 WP_192369290.1 71706..73643(+) (hexB) [Streptococcus suis strain YSJ17]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCAGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTCAAAA
TGATTCAAATTACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAATCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCCTCCATTGCTTCTGTCAG
TCATATAGTCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAT
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCCTT
TGTCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATCAATGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCGCTGGCAGTCATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAGGCAAGACTTTTTTTTAA
AACCAGATGTTGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCTACATCTGTTCAATTTGCAGAACGTCAATCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGTGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGAGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CCTACTTGTTTGCGCAAGGTAAGACAGGACTTTATATCATTGACCAGCACGCCGCACAGGAGCGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCGGCTCAACAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTCGTCCACAAAATGGATGCCCTTCGTCAAGTTGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGGGTCTGGCATTTATGAGATGTGCGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCGATCAAGGCCAATCA
TGCTCTGGATGATTACTCGGCGCGTGATTTACTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGTC
GCCCAGTCTTAGTACATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGA
GAGTTGGGGAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(447-589)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.462

100

0.73