Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   RK60_RS14360 Genome accession   NZ_CP026968
Coordinates   2730021..2731382 (-) Length   453 a.a.
NCBI ID   WP_016170667.1    Uniprot ID   -
Organism   Staphylococcus aureus strain FDAARGOS_1     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2721651..2731382 2730021..2731382 within 0


Gene organization within MGE regions


Location: 2721651..2731382
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RK60_RS14315 (RK60_14315) mecA 2721651..2723660 (-) 2010 WP_063852655.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  RK60_RS14320 (RK60_14320) - 2723757..2724743 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  RK60_RS14325 (RK60_14325) - 2724733..2724975 (+) 243 Protein_2671 type I restriction enzyme endonuclease domain-containing protein -
  RK60_RS14330 (RK60_14330) - 2724966..2726576 (-) 1611 Protein_2672 IS1182 family transposase -
  RK60_RS14335 (RK60_14335) - 2726625..2727131 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  RK60_RS14340 (RK60_14340) - 2727147..2727458 (-) 312 WP_016170671.1 DUF960 family protein -
  RK60_RS14350 (RK60_14350) - 2727545..2727895 (-) 351 WP_016170669.1 SAUGI family uracil-DNA glycosylase inhibitor -
  RK60_RS14355 (RK60_14355) ccrB 2728396..2730024 (-) 1629 WP_016170668.1 cassette chromosome recombinase CcrB Machinery gene
  RK60_RS14360 (RK60_14360) ccrA 2730021..2731382 (-) 1362 WP_016170667.1 cassette chromosome recombinase CcrA Machinery gene

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 53527.41 Da        Isoelectric Point: 10.0266

>NTDB_id=274079 RK60_RS14360 WP_016170667.1 2730021..2731382(-) (ccrA) [Staphylococcus aureus strain FDAARGOS_1]
MEEVIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVTFYDDKRSGRNTKRSGYKKIVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHVTIISVNDGYFDLSKEFDRFRLNILMSLAEMESNNISEQTRNGIREKAKQGKLITTHAPFGYRYR
QGHFVVYEEEVHTVKAVYRLYLQGLGYKKISQHLDNNSKLIPRKPYQVRNILLNPNYCGRVINKYGTFNNIVPPIIDVDT
FEEAQERRIHKQHNRSNSRNKLKRRIKCPYCQSTLTNLTIKKEHHSLRYYVCPKNMNDAYRTCPFKGINAPELESKVLDT
CKKYFEEQSFHNRLNDTILKVLKQQQMKHRQSHLTQEQLIEKLAQNQIDIETFKRLSTSYESEERYSNYSHKQMAEAVRH
VIKDKLTLETIAPLIDDITITQTKQLQRIYFKNSPFNIVEQSHLITPERNEVI

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=274079 RK60_RS14360 WP_016170667.1 2730021..2731382(-) (ccrA) [Staphylococcus aureus strain FDAARGOS_1]
ATGGAAGAAGTTATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACTGCTAAGCAATATGGATGGTCTAATGTGACATTTTATGATGATAAGAGAAGCGGTCGAAATACAAAACGTTCAGGCT
ATAAAAAAATAGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGTCTGAATCGACTCCATCGTAAT
TTGAAAAATGCTATACAATTCTTTGAAATTTGCAAAAAGCATCACGTCACAATCATCAGCGTGAATGATGGTTATTTTGA
CTTATCTAAAGAATTTGATCGCTTTCGCCTAAACATACTTATGAGTCTAGCTGAAATGGAGTCTAATAATATCAGTGAAC
AGACACGAAATGGGATAAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCACCTTTTGGCTATCGTTATAGA
CAAGGTCATTTTGTTGTATATGAAGAAGAAGTCCATACAGTCAAAGCAGTTTATCGCTTGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTAGATAATAATTCTAAGCTTATTCCACGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGTGGTCGTGTCATCAATAAGTATGGAACGTTTAATAATATCGTTCCGCCTATTATTGATGTTGATACG
TTTGAAGAAGCACAAGAGCGGCGTATTCATAAACAACACAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACAATAAAAAAAGAACATCATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAGGTATCAATGCACCAGAACTTGAAAGTAAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAATCGATTGAATGACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCACAGACAATCACATCTAACACAAGAACAACTCATCGAAAAATTAGCACAAAATCAAATTGACATAGAAACATTTA
AACGGTTATCTACTAGCTATGAAAGTGAAGAACGTTACTCTAATTATTCACATAAACAAATGGCCGAAGCAGTCCGTCAT
GTTATCAAAGATAAATTGACATTAGAAACCATAGCACCTTTGATTGATGACATTACAATAACTCAAACTAAACAGTTACA
AAGAATCTACTTTAAAAATAGTCCATTCAATATCGTTGAACAATCGCATTTAATAACTCCTGAAAGGAATGAAGTCATAT
GA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(168-248)

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

55.305

97.792

0.541
  ccrA Staphylococcus aureus N315

51.693

97.792

0.506

Multiple sequence alignment