Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   RK60_RS14355 Genome accession   NZ_CP026968
Coordinates   2728396..2730024 (-) Length   542 a.a.
NCBI ID   WP_016170668.1    Uniprot ID   -
Organism   Staphylococcus aureus strain FDAARGOS_1     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2721651..2731382 2728396..2730024 within 0


Gene organization within MGE regions


Location: 2721651..2731382
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RK60_RS14315 (RK60_14315) mecA 2721651..2723660 (-) 2010 WP_063852655.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  RK60_RS14320 (RK60_14320) - 2723757..2724743 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  RK60_RS14325 (RK60_14325) - 2724733..2724975 (+) 243 Protein_2671 type I restriction enzyme endonuclease domain-containing protein -
  RK60_RS14330 (RK60_14330) - 2724966..2726576 (-) 1611 Protein_2672 IS1182 family transposase -
  RK60_RS14335 (RK60_14335) - 2726625..2727131 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  RK60_RS14340 (RK60_14340) - 2727147..2727458 (-) 312 WP_016170671.1 DUF960 family protein -
  RK60_RS14350 (RK60_14350) - 2727545..2727895 (-) 351 WP_016170669.1 SAUGI family uracil-DNA glycosylase inhibitor -
  RK60_RS14355 (RK60_14355) ccrB 2728396..2730024 (-) 1629 WP_016170668.1 cassette chromosome recombinase CcrB Machinery gene
  RK60_RS14360 (RK60_14360) ccrA 2730021..2731382 (-) 1362 WP_016170667.1 cassette chromosome recombinase CcrA Machinery gene

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62405.78 Da        Isoelectric Point: 9.7442

>NTDB_id=274078 RK60_RS14355 WP_016170668.1 2728396..2730024(-) (ccrB) [Staphylococcus aureus strain FDAARGOS_1]
MKQLKKKRIGLYARVSTEMQTDGYSIQGQLNQLTEYCQFQGYEVVDEYTDRGISGKTMQRPELQRMLKDANEGKLDCIMV
YKTNRLARNTSDLLNIVEELYKINVEFFSLTEKIEIASSTGKLMLQILASFAEFERNTIVENVYNGQRQRAIEGYYQGNL
PLGYDKVPDSKKELMINQHEANIVKYIFKSYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDKALWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVLEKYVMDQILEIIKSKKVLKQLVEKVNKKSQIDVSSLNHDIAYKQSQCEE
IKAKMHTLTKTIEDSPDLDSVLKPTILSYQDELNQINNQIHQLEQDKQAEAPHYDADMIANVLQAIFKDIDKLEKSQLKS
LYLTVIDRIDIRKHEHHKKQFYVTLKLNNDIIKQLFDNHPLDEVLLSTSSLFLSQTLYITIE

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=274078 RK60_RS14355 WP_016170668.1 2728396..2730024(-) (ccrB) [Staphylococcus aureus strain FDAARGOS_1]
ATGAAACAACTCAAAAAGAAACGTATTGGATTATACGCACGTGTATCAACTGAAATGCAAACGGATGGTTACAGTATTCA
AGGTCAATTAAACCAACTTACAGAGTATTGTCAATTTCAAGGATATGAAGTCGTTGATGAATATACCGATCGAGGTATAT
CGGGTAAAACAATGCAACGTCCAGAATTACAACGTATGTTAAAAGATGCCAACGAAGGTAAATTAGATTGTATTATGGTC
TACAAAACCAATCGTTTAGCTAGAAATACCTCAGATTTGTTAAATATTGTCGAGGAATTGTATAAGATTAATGTCGAATT
TTTTAGTCTCACTGAAAAAATAGAAATTGCCAGCTCCACAGGTAAGTTGATGCTCCAAATTTTAGCCAGCTTCGCAGAAT
TTGAAAGAAATACGATTGTAGAGAATGTCTACAATGGCCAAAGACAACGTGCGATTGAAGGTTATTATCAAGGTAATTTG
CCTCTAGGCTATGATAAAGTACCTGATAGTAAAAAAGAGCTCATGATTAATCAACATGAAGCGAATATTGTTAAATATAT
CTTTAAGTCATACGCCAAAGGTCATGGTTATCGTAAGATTGCGAACGCATTGAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCGTTTAGTATTTCATCCATTACTTATATCATCTCAAACCCTTTTTATATTGGAAAGATACAGTTTGCGAAGTAT
AGACACTGGAGCGATAAGAGACGAAAAGGACTCAATGAGGAACCCATTATTGCTGATGGTAAGCATGCACCTATTATTGA
TAAAGCTTTATGGGATAAAGTACAGTTTAAACGCCAAGAGAGTCGCAAGAAACCTCAAGTTCATGGTAAAGGGACCAATC
TACTGACTGGAATTGTAAAGTGCCCAAAATGTGGTGCAGCCATGGCGGCAAGTAATACAACCAATACGTTAAAAGATGGC
ACTAAGAAAAGAATCAGATATTACTCATGTAGTAATTTTAGAAACAAAGGTTCTAAAGTATGTTCAGCCAATAGTGTTAG
AGCAGATGTATTAGAAAAATATGTTATGGATCAGATATTGGAAATTATCAAAAGTAAAAAGGTATTGAAACAATTGGTTG
AAAAGGTAAATAAAAAAAGTCAAATAGACGTCTCTTCTTTGAATCATGATATTGCCTATAAACAGTCACAATGTGAAGAA
ATAAAAGCCAAAATGCATACACTAACGAAAACCATCGAAGACTCACCTGACTTAGATAGCGTATTGAAACCAACAATACT
TAGCTACCAAGATGAATTGAATCAAATAAATAATCAAATACATCAACTAGAACAAGATAAACAAGCAGAAGCTCCACATT
ATGATGCTGATATGATTGCCAACGTACTACAAGCAATATTCAAAGATATAGACAAATTAGAGAAATCTCAGTTGAAATCA
CTCTATCTGACAGTTATCGATCGTATTGATATCCGAAAACATGAACATCATAAGAAGCAATTTTATGTTACGCTCAAATT
GAATAACGATATTATTAAACAACTATTTGATAATCATCCACTTGACGAAGTGCTCCTTAGCACTTCGTCTTTATTTTTGT
CCCAAACTTTATATATAACTATTGAATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(11-154)

Ogr/Delta-like zinc finger (Ogr_Delta)

(300-355)

Recombinase (Recombinase)

(179-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

72.694

100

0.727

Multiple sequence alignment