Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   D1369_RS18780 Genome accession   NZ_CP031969
Coordinates   4120575..4121258 (-) Length   227 a.a.
NCBI ID   WP_007383571.1    Uniprot ID   B5HVT9
Organism   Streptomyces sp. CC0208     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4115575..4126258
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1369_RS18750 - 4116587..4116787 (-) 201 WP_007383577.1 DUF397 domain-containing protein -
  D1369_RS18755 - 4116787..4117029 (-) 243 WP_342364923.1 hypothetical protein -
  D1369_RS18760 - 4117002..4117232 (+) 231 Protein_3714 ATP-binding protein -
  D1369_RS18765 - 4117328..4118410 (+) 1083 WP_037900896.1 MerR family transcriptional regulator -
  D1369_RS18770 vraR 4118440..4119105 (-) 666 WP_007383573.1 response regulator transcription factor Regulator
  D1369_RS18775 - 4119102..4120451 (-) 1350 WP_086023212.1 histidine kinase -
  D1369_RS18780 vraR 4120575..4121258 (-) 684 WP_007383571.1 response regulator transcription factor Regulator
  D1369_RS18785 - 4121255..4122607 (-) 1353 WP_240436083.1 histidine kinase -
  D1369_RS18790 - 4122618..4123859 (-) 1242 WP_007383569.1 acyltransferase -
  D1369_RS18795 - 4123852..4124850 (-) 999 WP_037903528.1 alpha/beta hydrolase -
  D1369_RS18800 - 4125204..4126136 (-) 933 WP_118082527.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24453.16 Da        Isoelectric Point: 4.8664

>NTDB_id=273840 D1369_RS18780 WP_007383571.1 4120575..4121258(-) (vraR) [Streptomyces sp. CC0208]
MTSGTSADIRVLIADDQQMVRQGFSVLLGAQPGIEVVGQAVDGLDAIAKVDELVPDVVLMDIRMPELGGIEATRRITGER
PEIRVLVLTTFDLDEYVYEALRAGASGFLLKDASAEQLAEAVRVVAAGDALLAPGITRRLIAEFSRLDHRPRAPLKTRVG
ELTERETEVLALIAQGLSNAEIAGRLVVAEQTVKTHVGRILVKLGLRDRTQAAVFAYESGLVRPSGY

Nucleotide


Download         Length: 684 bp        

>NTDB_id=273840 D1369_RS18780 WP_007383571.1 4120575..4121258(-) (vraR) [Streptomyces sp. CC0208]
ATGACGAGCGGCACCAGCGCAGACATCCGCGTACTGATCGCGGACGATCAGCAGATGGTCCGGCAGGGCTTCAGCGTGCT
GCTGGGCGCCCAGCCCGGCATCGAGGTGGTCGGGCAGGCGGTCGACGGACTGGACGCGATCGCCAAGGTCGACGAACTCG
TCCCGGACGTCGTCCTGATGGACATCCGCATGCCCGAGCTGGGCGGCATCGAGGCCACCCGCCGCATCACCGGCGAGCGC
CCGGAGATCAGGGTCCTGGTGCTGACCACCTTCGACCTCGACGAGTACGTCTACGAGGCCCTGCGGGCCGGTGCCTCCGG
GTTCCTGCTGAAGGACGCCTCCGCGGAGCAGCTCGCTGAAGCGGTGCGGGTGGTGGCGGCCGGGGACGCACTGCTCGCGC
CCGGCATCACCCGGCGGCTGATCGCCGAGTTCTCCCGTCTCGACCACCGGCCCCGCGCTCCGCTCAAGACCCGGGTCGGC
GAGCTGACCGAGCGGGAGACGGAGGTCCTCGCCCTGATCGCGCAGGGCCTGTCGAACGCCGAGATCGCCGGGCGGCTCGT
GGTGGCCGAGCAGACCGTGAAGACGCACGTGGGTCGCATCCTGGTGAAGCTGGGCCTCAGGGACCGTACGCAGGCGGCGG
TGTTCGCCTACGAGTCGGGGCTGGTGCGGCCGTCGGGCTACTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(162-216)

Response regulator receiver domain (Response_reg)

(11-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B5HVT9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.116

94.714

0.427
  degU Bacillus subtilis subsp. subtilis str. 168

41.256

98.238

0.405

Multiple sequence alignment