Detailed information NTG0273772

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: RL06_RS12280
• Genome accession: NZ_CP026953
• Coordinates: 2299166..2300152 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain FDAARGOS_48
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 2294166..2305152

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RL06_RS12255 (RL06_12255)	opp4B	2294380..2295342 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
RL06_RS12260 (RL06_12260)	opp4C	2295354..2296235 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
RL06_RS12265 (RL06_12265)	trpS	2296277..2297266 (-)	990	WP_016170570.1	tryptophan--tRNA ligase	-
RL06_RS12270 (RL06_12270)	spxA	2297560..2297955 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
RL06_RS12275 (RL06_12275)	mecA	2298326..2299045 (+)	720	WP_001217728.1	adaptor protein MecA	-
RL06_RS12280 (RL06_12280)	coiA	2299166..2300152 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
RL06_RS12285 (RL06_12285)	pepF	2300200..2302008 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
RL06_RS12290 (RL06_12290)	yjbH	2302468..2303274 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
RL06_RS12295 (RL06_12295)	-	2303297..2303662 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
RL06_RS12300 (RL06_12300)	-	2303766..2304359 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
RL06_RS12305 (RL06_12305)	-	2304545..2304892 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=273772 RL06_RS12280 WP_000959282.1 2299166..2300152(+) (coiA) [Staphylococcus aureus strain FDAARGOS_48]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=273772 RL06_RS12280 WP_000959282.1 2299166..2300152(+) (coiA) [Staphylococcus aureus strain FDAARGOS_48]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976