Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   CCU04_RS10580 Genome accession   NZ_CP031908
Coordinates   2115706..2116362 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O103:H2 strain FWSEC0007     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2110706..2121362
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCU04_RS10550 (CCU04_011135) dcyD 2111586..2112572 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  CCU04_RS10555 (CCU04_011140) tcyL 2112587..2113255 (+) 669 WP_001158206.1 cystine ABC transporter permease -
  CCU04_RS10560 (CCU04_011145) tcyN 2113252..2114004 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  CCU04_RS10565 (CCU04_011150) sdiA 2114234..2114956 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  CCU04_RS10570 (CCU04_011155) yecF 2115023..2115247 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  CCU04_RS10575 yecU 2115234..2115410 (-) 177 WP_000590347.1 protein YecU -
  CCU04_RS28755 - 2115493..2115564 (-) 72 Protein_2031 transcriptional regulator -
  CCU04_RS10580 (CCU04_011160) letA 2115706..2116362 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  CCU04_RS10585 (CCU04_011165) uvrC 2116359..2118191 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  CCU04_RS10590 (CCU04_011170) pgsA 2118248..2118796 (+) 549 WP_001160189.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  CCU04_RS10610 (CCU04_011190) - 2119791..2120072 (+) 282 WP_071529678.1 hypothetical protein -
  CCU04_RS10615 (CCU04_011195) - 2120262..2120402 (-) 141 WP_000078920.1 Hok/Gef family protein -
  CCU04_RS10620 (CCU04_011200) - 2120592..2120852 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=273188 CCU04_RS10580 WP_000611335.1 2115706..2116362(+) (letA) [Escherichia coli O103:H2 strain FWSEC0007]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=273188 CCU04_RS10580 WP_000611335.1 2115706..2116362(+) (letA) [Escherichia coli O103:H2 strain FWSEC0007]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment