Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA2   Type   Machinery gene
Locus tag   NMC_RS09945 Genome accession   NC_008767
Coordinates   1917143..1917838 (-) Length   231 a.a.
NCBI ID   WP_002248140.1    Uniprot ID   A1KVZ3
Organism   Neisseria meningitidis FAM18     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1916101..1917066 1917143..1917838 flank 77


Gene organization within MGE regions


Location: 1916101..1917838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMC_RS09940 (NMC1884) - 1916101..1917066 (+) 966 WP_002216744.1 IS30-like element IS1655 family transposase -
  NMC_RS09945 (NMC1885) dsbA2 1917143..1917838 (-) 696 WP_002248140.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 25378.89 Da        Isoelectric Point: 5.3625

>NTDB_id=27255 NMC_RS09945 WP_002248140.1 1917143..1917838(-) (dsbA2) [Neisseria meningitidis FAM18]
MKLKTLALTSLTLLALAACSKQAETSVPADSVQSSSSAPAAPAPLTEGVNYTVLSTPIPQQQAGKVEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEASESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide


Download         Length: 696 bp        

>NTDB_id=27255 NMC_RS09945 WP_002248140.1 1917143..1917838(-) (dsbA2) [Neisseria meningitidis FAM18]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGCGT
TCCGGCAGACAGCGTCCAAAGCAGCTCATCTGCTCCGGCAGCCCCAGCCCCATTGACCGAAGGCGTGAACTACACTGTAT
TGTCCACGCCTATCCCGCAACAGCAGGCCGGCAAAGTCGAAGTCTTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTTCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATCGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCCGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(64-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A1KVZ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA2 Neisseria meningitidis MC58

97.835

100

0.978
  dsbA1 Neisseria meningitidis MC58

70.815

100

0.714

Multiple sequence alignment