Detailed information NTG0271458

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: C4N11_RS10285
• Genome accession: NZ_CP026670
• Coordinates: 1932483..1933520 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain endophthalmitis isolate 335
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1927483..1938520

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C4N11_RS10260 (C4N11_10260)	-	1928284..1929615 (-)	1332	WP_000390046.1	hemolysin family protein	-
C4N11_RS10265 (C4N11_10265)	endA	1929844..1930668 (-)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
C4N11_RS10270 (C4N11_10270)	-	1930707..1930895 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
C4N11_RS10275 (C4N11_10275)	murA	1930888..1932171 (-)	1284	WP_000358033.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
C4N11_RS10280 (C4N11_10280)	-	1932195..1932425 (-)	231	WP_000615437.1	DUF1146 family protein	-
C4N11_RS10285 (C4N11_10285)	sepM	1932483..1933520 (-)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
C4N11_RS10290 (C4N11_10290)	coaD	1933504..1933992 (-)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
C4N11_RS10295 (C4N11_10295)	rsmD	1933982..1934521 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
C4N11_RS10300 (C4N11_10300)	asnA	1934586..1935578 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
C4N11_RS10310 (C4N11_10310)	-	1935690..1936373 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
C4N11_RS10315 (C4N11_10315)	-	1936429..1937169 (-)	741	WP_000152701.1	RNA methyltransferase	-
C4N11_RS10320 (C4N11_10320)	-	1937203..1937481 (+)	279	WP_001174613.1	acylphosphatase	-
C4N11_RS10325 (C4N11_10325)	yidC	1937559..1938485 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=271458 C4N11_RS10285 WP_000727280.1 1932483..1933520(-) (sepM) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=271458 C4N11_RS10285 WP_000727280.1 1932483..1933520(-) (sepM) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591