Detailed information NTG0271449

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: C4N11_RS09760
• Genome accession: NZ_CP026670
• Coordinates: 1848246..1849313 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159556.1
• Uniprot ID: A0A0B7LLF7
• Organism: Streptococcus pneumoniae strain endophthalmitis isolate 335
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1843246..1854313

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C4N11_RS09735 (C4N11_09735)	treR	1843417..1844127 (+)	711	WP_000760670.1	trehalose operon repressor	Regulator
C4N11_RS09740 (C4N11_09740)	-	1844160..1844963 (-)	804	WP_000202629.1	ABC transporter ATP-binding protein	-
C4N11_RS09745 (C4N11_09745)	-	1844976..1845869 (-)	894	WP_001012089.1	ABC transporter permease	-
C4N11_RS09750 (C4N11_09750)	-	1845881..1846818 (-)	938	Protein_1849	ABC transporter substrate-binding protein	-
C4N11_RS09755 (C4N11_09755)	amiF	1847309..1848235 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
C4N11_RS09760 (C4N11_09760)	amiE	1848246..1849313 (-)	1068	WP_000159556.1	ABC transporter ATP-binding protein	Regulator
C4N11_RS09765 (C4N11_09765)	amiD	1849322..1850248 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
C4N11_RS09770 (C4N11_09770)	-	1850248..1851744 (-)	1497	Protein_1853	ABC transporter permease	-
C4N11_RS09780 (C4N11_09780)	amiA3	1851811..1853790 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=271449 C4N11_RS09760 WP_000159556.1 1848246..1849313(-) (amiE) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=271449 C4N11_RS09760 WP_000159556.1 1848246..1849313(-) (amiE) [Streptococcus pneumoniae strain endophthalmitis isolate 335]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTATTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGAACTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCGAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0B7LLF7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541