Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   D0819_RS04410 Genome accession   NZ_CP031784
Coordinates   826256..828139 (+) Length   627 a.a.
NCBI ID   WP_153256757.1    Uniprot ID   -
Organism   Bacillus subtilis strain HMNig-2     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 821256..833139
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D0819_RS04395 (D0819_04405) ymcA 822293..822724 (+) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator
  D0819_RS04400 (D0819_04410) cotE 822986..823531 (+) 546 WP_003231833.1 outer spore coat protein CotE -
  D0819_RS04405 (D0819_04415) hexA 823664..826240 (+) 2577 WP_153256756.1 DNA mismatch repair protein MutS Machinery gene
  D0819_RS04410 (D0819_04420) hexB 826256..828139 (+) 1884 WP_153256757.1 DNA mismatch repair endonuclease MutL Machinery gene
  D0819_RS04415 (D0819_04425) ymzD 828537..828992 (-) 456 WP_021479270.1 regulatory YrvL family protein -
  D0819_RS04420 (D0819_04430) - 829147..829704 (-) 558 WP_014479830.1 hypothetical protein -
  D0819_RS04425 (D0819_04435) pksA 829825..830442 (+) 618 WP_015715907.1 TetR/AcrR family transcriptional regulator -
  D0819_RS04430 (D0819_04440) pksB 830632..831309 (+) 678 WP_015715908.1 MBL fold metallo-hydrolase -
  D0819_RS04435 (D0819_04445) - 831420..831686 (+) 267 WP_120363368.1 hypothetical protein -
  D0819_RS04440 (D0819_04450) fabD 831683..832549 (+) 867 WP_021479264.1 ACP S-malonyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70610.56 Da        Isoelectric Point: 5.6795

>NTDB_id=271246 D0819_RS04410 WP_153256757.1 826256..828139(+) (hexB) [Bacillus subtilis strain HMNig-2]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQLPKKSAPVIKNEQQFITFDEKPPERKVPEKAHAPSYSPMKLSSVVKEPVDAEEELPPLQFDAPPI
VDQEQTLEVSDISEELPETFEQECHEEQQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQDMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=271246 D0819_RS04410 WP_153256757.1 826256..828139(+) (hexB) [Bacillus subtilis strain HMNig-2]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTAGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACGGATGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGTGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGGAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAACGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATTCGTGACGGA
ATTAAAGATGTATTTAAACAGCAGCAGCTGATTCCGAGTGCCCAGCTCCCGAAAAAATCGGCACCTGTAATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAGAAAAGTACCGGAAAAAGCGCATGCGCCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGGTTGATGCGGAGGAAGAATTGCCTCCTCTCCAATTTGATGCTCCTCCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATATTTCAGAAGAACTGCCTGAAACATTTGAGCAGGAATGCCATGAGGA
ACAGCAGCAGCCAGCGTCTGAGCGGGTTCCGATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTGTATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTTCGAGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTGCAGGATATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTTGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCGG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTCATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGATGA
AATCAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATTCACC
ACTCGACATATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

MutL C terminal dimerisation domain (MutL_C)

(442-583)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.342

100

0.466

Multiple sequence alignment