Detailed information
Bioinformatically predicted
Overview
| Name | recA | Type | Machinery gene |
| Locus tag | C4E25_RS06565 | Genome accession | NZ_CP026613 |
| Coordinates | 1343776..1344822 (+) | Length | 348 a.a. |
| NCBI ID | WP_003419530.1 | Uniprot ID | A0AAX3GVV5 |
| Organism | Clostridioides difficile strain R1 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1338986..1389620 | 1343776..1344822 | within | 0 |
Gene organization within MGE regions
Location: 1338986..1389620
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C4E25_RS06550 (C4E25_18010) | mnmH | 1340594..1341652 (+) | 1059 | WP_003419524.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
| C4E25_RS06555 (C4E25_18015) | rimO | 1341646..1342980 (+) | 1335 | WP_003419527.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| C4E25_RS06560 (C4E25_18020) | pgsA | 1342967..1343509 (+) | 543 | WP_009905407.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| C4E25_RS06565 (C4E25_18025) | recA | 1343776..1344822 (+) | 1047 | WP_003419530.1 | recombinase RecA | Machinery gene |
| C4E25_RS06570 (C4E25_18030) | rny | 1344998..1346539 (+) | 1542 | WP_003428216.1 | ribonuclease Y | - |
| C4E25_RS06575 (C4E25_18035) | - | 1346849..1349185 (+) | 2337 | WP_003419542.1 | diguanylate cyclase | - |
| C4E25_RS06585 (C4E25_18045) | - | 1349991..1350089 (+) | 99 | Protein_1174 | transposase | - |
| C4E25_RS06590 (C4E25_18050) | tnpB | 1350091..1351209 (+) | 1119 | WP_041160402.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| C4E25_RS06600 (C4E25_18060) | - | 1351541..1353322 (+) | 1782 | WP_003419546.1 | UvrD-helicase domain-containing protein | - |
| C4E25_RS06605 (C4E25_18065) | lepB | 1353402..1353932 (-) | 531 | WP_009905409.1 | signal peptidase I | - |
| C4E25_RS06610 (C4E25_18070) | - | 1353972..1354796 (-) | 825 | WP_009905410.1 | undecaprenyl-diphosphate phosphatase | - |
| C4E25_RS06615 (C4E25_18075) | - | 1355053..1355964 (+) | 912 | WP_022615208.1 | tyrosine-type recombinase/integrase | - |
| C4E25_RS06620 (C4E25_18080) | purB | 1356103..1357548 (+) | 1446 | WP_003419557.1 | adenylosuccinate lyase | - |
| C4E25_RS06625 (C4E25_18085) | - | 1357849..1358301 (+) | 453 | WP_003419561.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| C4E25_RS06630 (C4E25_18090) | - | 1358520..1359716 (-) | 1197 | WP_003419570.1 | pyridoxal phosphate-dependent aminotransferase | - |
| C4E25_RS06635 (C4E25_18095) | galT | 1360101..1361051 (+) | 951 | WP_003419573.1 | galactose-1-phosphate uridylyltransferase | - |
| C4E25_RS06640 (C4E25_18100) | - | 1361172..1361924 (+) | 753 | WP_003419575.1 | exodeoxyribonuclease III | - |
| C4E25_RS06645 (C4E25_18105) | - | 1362016..1362792 (-) | 777 | WP_003419578.1 | 3'-5' exonuclease | - |
| C4E25_RS06650 (C4E25_18110) | - | 1363107..1365005 (+) | 1899 | WP_003419583.1 | glutamine synthetase | - |
| C4E25_RS06655 (C4E25_18115) | - | 1365133..1366254 (-) | 1122 | WP_003419591.1 | MGDG synthase family glycosyltransferase | - |
| C4E25_RS06660 (C4E25_18120) | - | 1366453..1366785 (+) | 333 | WP_009905416.1 | PadR family transcriptional regulator | - |
| C4E25_RS06665 (C4E25_18125) | - | 1366772..1367830 (+) | 1059 | WP_003419595.1 | DUF1700 domain-containing protein | - |
| C4E25_RS06670 (C4E25_18130) | - | 1367823..1368893 (+) | 1071 | WP_003419596.1 | DUF4097 family beta strand repeat-containing protein | - |
| C4E25_RS06675 (C4E25_18135) | - | 1368995..1369531 (+) | 537 | WP_003419598.1 | hypothetical protein | - |
| C4E25_RS06680 (C4E25_18140) | - | 1369651..1370358 (+) | 708 | WP_009905418.1 | lantibiotic protection ABC transporter ATP-binding protein | - |
| C4E25_RS06685 (C4E25_18145) | - | 1370360..1371079 (+) | 720 | WP_003419603.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| C4E25_RS06690 (C4E25_18150) | - | 1371081..1371851 (+) | 771 | WP_003419609.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| C4E25_RS06695 (C4E25_18155) | - | 1371985..1373376 (+) | 1392 | WP_029158131.1 | sensor histidine kinase | - |
| C4E25_RS06700 (C4E25_18160) | - | 1373452..1374273 (-) | 822 | WP_003419615.1 | pyridoxamine kinase | - |
| C4E25_RS06705 (C4E25_18165) | - | 1374524..1375678 (+) | 1155 | WP_009905420.1 | amidase domain-containing protein | - |
| C4E25_RS06710 (C4E25_18170) | - | 1375861..1376061 (+) | 201 | WP_003419624.1 | cold-shock protein | - |
| C4E25_RS06715 (C4E25_18175) | - | 1376482..1376910 (+) | 429 | WP_009889129.1 | CBS domain-containing protein | - |
| C4E25_RS06720 (C4E25_18180) | - | 1377053..1377808 (-) | 756 | WP_009889131.1 | peptidylprolyl isomerase | - |
| C4E25_RS06730 (C4E25_18190) | - | 1378509..1379015 (-) | 507 | WP_003419636.1 | ImmA/IrrE family metallo-endopeptidase | - |
| C4E25_RS06735 (C4E25_18195) | - | 1379097..1379417 (-) | 321 | WP_003419639.1 | XRE family transcriptional regulator | - |
| C4E25_RS06740 (C4E25_18200) | - | 1379586..1379783 (+) | 198 | WP_003419641.1 | helix-turn-helix transcriptional regulator | - |
| C4E25_RS06745 (C4E25_18205) | - | 1379887..1380327 (+) | 441 | WP_003419643.1 | hypothetical protein | - |
| C4E25_RS06750 (C4E25_18210) | - | 1380576..1381019 (+) | 444 | WP_003419644.1 | phage tail terminator family protein | - |
| C4E25_RS06755 (C4E25_18215) | - | 1381024..1382088 (+) | 1065 | WP_003419645.1 | phage tail sheath subtilisin-like domain-containing protein | - |
| C4E25_RS06760 (C4E25_18220) | - | 1382102..1382530 (+) | 429 | WP_003419646.1 | phage tail tube protein | - |
| C4E25_RS06765 (C4E25_18225) | - | 1382644..1383090 (+) | 447 | WP_003419647.1 | phage tail assembly chaperone | - |
| C4E25_RS06775 (C4E25_18235) | - | 1383284..1385737 (+) | 2454 | WP_003419649.1 | hypothetical protein | - |
| C4E25_RS06780 (C4E25_18240) | - | 1385737..1386159 (+) | 423 | WP_003419651.1 | phage baseplate protein | - |
| C4E25_RS06785 (C4E25_18245) | - | 1386441..1387970 (+) | 1530 | WP_003419653.1 | NlpC/P60 family protein | - |
| C4E25_RS06790 (C4E25_18250) | - | 1387986..1388312 (+) | 327 | WP_003419655.1 | DUF2577 family protein | - |
| C4E25_RS06795 (C4E25_18255) | - | 1388312..1388740 (+) | 429 | WP_003419656.1 | DUF2634 domain-containing protein | - |
Sequence
Protein
Download Length: 348 a.a. Molecular weight: 37387.68 Da Isoelectric Point: 4.8236
>NTDB_id=270848 C4E25_RS06565 WP_003419530.1 1343776..1344822(+) (recA) [Clostridioides difficile strain R1]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTNEI
DEKVRAFYNLNEEHEEAGNSVSKEIVEE
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTNEI
DEKVRAFYNLNEEHEEAGNSVSKEIVEE
Nucleotide
Download Length: 1047 bp
>NTDB_id=270848 C4E25_RS06565 WP_003419530.1 1343776..1344822(+) (recA) [Clostridioides difficile strain R1]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGATATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCACTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATACGCAAAAGC
TTTGGGCGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGACTCTCACGTAGGGTTACAAGCTAGACTTATGTCGCAAGCTCTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCATTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGACACAATAAAACAAGGAGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTCGTTAAAAATAAAGTAGCACCTCCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTCTAGATATAGCTGCTGATGTAGATATAGTAAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAGGATAATTTAGATTTAACTAATGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAAGCAGGTAATTCAGTATCAAAAGAAATTGTAGA
AGAATAA
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGATATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCACTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATACGCAAAAGC
TTTGGGCGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGACTCTCACGTAGGGTTACAAGCTAGACTTATGTCGCAAGCTCTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCATTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGACACAATAAAACAAGGAGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTCGTTAAAAATAAAGTAGCACCTCCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTCTAGATATAGCTGCTGATGTAGATATAGTAAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAGGATAATTTAGATTTAACTAATGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAAGCAGGTAATTCAGTATCAAAAGAAATTGTAGA
AGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.