Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   SGO_RS06930 Genome accession   NC_009785
Coordinates   1456866..1460516 (-) Length   1216 a.a.
NCBI ID   WP_012130498.1    Uniprot ID   A8AY33
Organism   Streptococcus gordonii str. Challis substr. CH1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1451866..1465516
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGO_RS06905 (SGO_1408) hisD 1452021..1453313 (-) 1293 WP_012130493.1 histidinol dehydrogenase -
  SGO_RS06910 (SGO_1409) hisG 1453310..1453954 (-) 645 WP_012130494.1 ATP phosphoribosyltransferase -
  SGO_RS06915 (SGO_1410) - 1453951..1454940 (-) 990 WP_012130495.1 ATP phosphoribosyltransferase regulatory subunit -
  SGO_RS06920 (SGO_1411) hisC 1454996..1456054 (-) 1059 WP_012130496.1 histidinol-phosphate transaminase -
  SGO_RS06925 (SGO_1412) - 1456527..1456832 (-) 306 WP_012130497.1 DUF4298 domain-containing protein -
  SGO_RS06930 (SGO_1413) rexA 1456866..1460516 (-) 3651 WP_012130498.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  SGO_RS06935 (SGO_1414) rexB 1460513..1463794 (-) 3282 WP_012130499.1 ATP-dependent nuclease subunit B Machinery gene

Sequence

Protein


Download         Length: 1216 a.a.        Molecular weight: 140370.13 Da        Isoelectric Point: 5.0905

>NTDB_id=27075 SGO_RS06930 WP_012130498.1 1456866..1460516(-) (rexA) [Streptococcus gordonii str. Challis substr. CH1]
MRKKSFLSPEEISQLQHFEATSSKEQKRTAEQIEAIYSSGQNILVSASAGSGKTFVMVQRIIDQILRGVSIQELFISTFT
VKAAGELKERLEKELSKVLKESQDEELKQHLAKQLAAIATADIGTMDSFTQKLLNKYGYLLGLAPNFRILQSASEQTMLQ
NEVFQQLFEQYYTGEQKEIFEKLVKNFTGKKKNISGFRQQVYAIYQFLQSTSNPQRWLQDFFLKGYEETDFSRERDKILQ
QVKGALFDLEDYFRFHLDNEGREFAGAKYQENVLLALDKLGSLQELSSEQDYFRVLKDVVLLSRASGGRALTITTRKEEL
KELADTFNQGRKERIEHLRGLESSIYQFEFLEKYQDDSLPLLDLLRDFMSDFTQTYLERKKTENAFEFGDISHFAIQILE
DFPQVRSFYQERYHEVMVDEYQDTNHTQERMLELLSNGYNRFMVGDIKQSIYRFRQADPQIFNDKFRLYQADPSQGKLIV
LKENFRSHVEVLEATNDVFKRLMDEQVGEINYDETHYLVAGNPTKASPDPKNRAEFLLYDSTVASEELSEESISAGEVSL
VIKEIIRLHEEEAVAFKDITLLTASRTRNDIILAEFAKHNIPLVPDGGEDNYLQSVEVMVMLDTLRTINNPLNDYALTAL
LKSAMFDFGEDELARIALQKSQEKSQENLYEKLENALTNQGLHPDLILPDHKKKLELFQKTLLSWRTFAKTHSLYDLIWK
IYQDRFYYEYVGALPNGAQRQANLYALSLRANDYEKSSFKGLSRFISMIDKILENQHDLASVPYAAPQDAVHLMTVHKSK
GLEFKYVFLLNMDKAFNRQDTSSSIILSRKNGIGIKYIADVEVEYPEKVKPRSIRLSMDTLPYQQNLEEIKLASLSEQMR
LLYVAMTRAETKLYLVGKGSQEKLEKRSWGQAEQGLLSASIRSQTTSFQDWLYAIQTVFSEDQLAFDLRFVRDEDLTADK
IGQIHHSNPFDADDLTDNRQSEDIGRALDILESVDRLNSQYRSAIELPSVRTPSQIKKFYEPIMDTEGMDIIDERVAFRP
QPNFDLPDFSRKAKVTGAQVGSAVHELMQRIPIDQKPDMAVLKLSLKQVQAEESVKKQIDLNKIASFFETRLGEILLANS
DKLHREAPFAMFKRDEISGQDFVLRGILDGYLLFEDRIILFDYKTDKYKEASELIARYHSQLDLYAQALSRSYGISQIEK
YLILLGGEQLQVVQVD

Nucleotide


Download         Length: 3651 bp        

>NTDB_id=27075 SGO_RS06930 WP_012130498.1 1456866..1460516(-) (rexA) [Streptococcus gordonii str. Challis substr. CH1]
ATGAGGAAGAAGTCTTTTTTAAGTCCAGAAGAAATCAGTCAGCTACAGCATTTTGAAGCCACTTCAAGTAAAGAACAGAA
ACGAACTGCTGAGCAGATTGAGGCTATTTATTCCTCAGGTCAAAACATCCTAGTCTCTGCATCAGCTGGGTCAGGGAAAA
CCTTTGTCATGGTTCAGAGGATTATTGACCAGATCCTCCGTGGAGTATCCATCCAGGAACTCTTCATCTCAACCTTTACC
GTAAAAGCGGCTGGAGAACTCAAGGAACGTCTAGAAAAAGAGTTAAGTAAAGTCCTCAAAGAAAGTCAGGATGAAGAACT
TAAACAGCACCTAGCCAAGCAGTTAGCTGCTATTGCCACGGCTGATATTGGGACCATGGACTCTTTCACACAAAAGCTTC
TTAATAAGTATGGCTATCTTCTAGGCTTGGCCCCTAATTTTCGTATTCTCCAGTCAGCTAGTGAGCAGACTATGCTACAA
AATGAAGTCTTTCAGCAGCTTTTTGAGCAATATTATACTGGTGAGCAGAAGGAAATTTTTGAAAAGTTAGTCAAAAATTT
CACGGGCAAGAAAAAGAACATCTCTGGTTTTCGCCAGCAAGTTTACGCTATTTACCAGTTTCTCCAATCAACCAGCAATC
CTCAGAGATGGTTGCAGGACTTTTTCCTTAAAGGCTATGAAGAGACAGATTTTTCTCGTGAGAGAGACAAAATTTTACAG
CAAGTGAAAGGTGCTCTCTTTGACCTCGAAGATTATTTCCGTTTTCATTTGGATAACGAGGGACGTGAATTTGCGGGAGC
TAAATACCAGGAAAATGTGTTGCTTGCGCTAGATAAACTGGGGAGTTTGCAGGAATTGTCCTCTGAGCAGGACTATTTCC
GCGTCTTAAAAGATGTGGTTCTTCTATCTCGGGCTAGTGGCGGCCGAGCCTTGACCATTACTACTCGCAAGGAAGAATTA
AAAGAGCTGGCTGATACCTTTAATCAAGGACGTAAAGAACGAATCGAGCATTTGCGAGGTCTGGAGTCCAGCATCTATCA
ATTTGAGTTCCTTGAGAAGTATCAGGATGATAGTCTACCTCTCTTAGATTTACTACGTGATTTCATGAGTGATTTTACTC
AGACTTATCTAGAACGTAAAAAAACAGAGAATGCTTTTGAGTTCGGGGATATCAGCCATTTTGCGATACAGATTCTAGAG
GACTTCCCACAGGTAAGAAGTTTTTATCAGGAGCGTTACCATGAGGTTATGGTTGATGAGTACCAGGATACTAACCACAC
CCAGGAGCGAATGTTGGAGCTCTTATCTAACGGCTATAATCGCTTTATGGTGGGAGATATCAAACAATCCATCTATCGTT
TTCGTCAAGCAGATCCCCAGATTTTCAATGATAAGTTTCGGCTTTATCAGGCAGATCCGAGCCAAGGGAAACTGATTGTC
CTCAAGGAGAATTTCCGTAGTCATGTAGAGGTGCTGGAAGCAACCAATGATGTCTTTAAGAGACTGATGGATGAGCAGGT
CGGGGAAATCAACTATGATGAGACCCATTATTTGGTGGCGGGAAATCCGACGAAAGCATCACCTGATCCAAAAAATAGGG
CTGAATTTCTCCTTTATGATTCGACGGTAGCAAGCGAGGAACTAAGCGAGGAAAGTATCTCAGCTGGAGAAGTGTCTCTA
GTTATCAAGGAAATCATTCGCCTGCATGAGGAAGAAGCGGTTGCCTTTAAGGACATTACTCTTTTAACGGCTTCTCGGAC
TCGAAATGATATAATCTTGGCTGAGTTTGCCAAGCACAATATCCCTCTTGTACCAGATGGAGGGGAAGACAATTACCTCC
AGTCTGTCGAGGTCATGGTCATGCTGGACACTTTGCGAACGATCAATAATCCCTTAAATGACTATGCCTTAACAGCACTA
CTCAAATCAGCAATGTTTGACTTTGGAGAAGATGAGCTGGCTCGAATAGCGCTACAGAAAAGTCAGGAAAAATCGCAGGA
AAATCTCTATGAGAAGTTAGAAAATGCCTTGACTAATCAAGGATTGCATCCAGACTTAATCTTGCCAGACCATAAAAAGA
AGCTAGAGCTCTTTCAAAAGACGCTCTTATCATGGCGAACCTTTGCTAAAACTCATTCTCTGTACGATTTGATTTGGAAG
ATTTATCAAGACCGCTTTTATTATGAATATGTTGGTGCCTTGCCCAATGGAGCACAGCGTCAAGCCAATCTCTATGCCCT
ATCACTCAGAGCTAATGACTACGAGAAATCAAGTTTTAAAGGCCTGTCTCGATTCATTAGTATGATTGATAAGATTTTAG
AGAACCAGCACGATTTGGCCAGCGTTCCCTATGCAGCACCGCAAGATGCGGTTCATCTGATGACAGTCCACAAGAGTAAG
GGACTAGAGTTCAAGTATGTCTTTCTGCTTAATATGGACAAGGCCTTTAACCGCCAAGATACCAGTTCTAGCATTATCTT
GAGTCGTAAAAATGGGATTGGGATTAAATATATCGCTGATGTAGAGGTTGAATATCCAGAAAAAGTGAAACCAAGATCAA
TCCGTTTGTCAATGGATACGCTACCCTACCAGCAAAATTTAGAAGAGATCAAGCTGGCTAGTCTTTCTGAGCAGATGCGC
TTGCTTTATGTAGCCATGACACGGGCTGAAACCAAGCTTTACTTGGTTGGAAAAGGTAGCCAAGAAAAACTTGAGAAACG
AAGTTGGGGACAGGCAGAACAGGGGCTTTTATCGGCTTCCATACGTAGTCAGACAACTTCTTTCCAAGATTGGCTTTATG
CTATCCAGACTGTTTTTTCAGAAGATCAGCTTGCTTTTGATTTGAGATTTGTCAGAGATGAAGATTTGACTGCTGACAAA
ATTGGCCAGATCCACCATTCAAATCCCTTTGATGCGGATGATTTGACAGACAACCGTCAGTCAGAAGATATCGGCAGGGC
TCTGGATATCTTAGAAAGTGTAGATCGATTAAATAGCCAATATCGCTCTGCCATTGAGCTACCTAGTGTGCGAACGCCAA
GCCAAATTAAGAAGTTCTATGAGCCGATTATGGATACGGAAGGCATGGATATCATAGATGAGCGAGTAGCTTTTCGGCCT
CAGCCTAACTTTGACTTGCCTGATTTTAGCCGGAAAGCCAAGGTGACCGGGGCTCAAGTCGGTAGTGCCGTTCATGAACT
CATGCAACGGATTCCTATAGATCAGAAGCCGGACATGGCAGTTTTAAAATTAAGTCTGAAACAGGTTCAAGCAGAAGAGT
CTGTGAAAAAACAGATTGACCTCAATAAGATTGCAAGTTTCTTTGAGACTCGGCTTGGTGAAATCTTGCTAGCTAACTCT
GATAAATTACATCGAGAAGCACCTTTTGCCATGTTTAAGAGGGACGAAATCAGTGGTCAGGACTTTGTTTTGCGGGGGAT
TTTGGATGGTTACCTGCTCTTTGAGGATCGAATTATCCTCTTTGATTACAAGACGGATAAATACAAGGAAGCATCTGAGT
TGATAGCTCGCTACCACAGTCAGCTAGACCTATATGCTCAAGCTCTCAGTCGTTCTTATGGCATTTCTCAGATTGAAAAA
TATTTGATTCTGCTGGGAGGTGAGCAGTTACAGGTAGTTCAGGTGGACTGA

Domains

Predicted by InterProScan.

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1056-1192)

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(29-465)

UvrD-like helicase C-terminal domain (UvrD_C)

(479-895)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AY33

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

60.887

100

0.609

Multiple sequence alignment