Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   SGO_RS04075 Genome accession   NC_009785
Coordinates   873477..875312 (+) Length   611 a.a.
NCBI ID   WP_012000286.1    Uniprot ID   A8AWG9
Organism   Streptococcus gordonii str. Challis substr. CH1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 868477..880312
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGO_RS04050 (SGO_0825) - 869308..869943 (+) 636 WP_012000281.1 hypothetical protein -
  SGO_RS04055 (SGO_0826) - 870034..870528 (+) 495 WP_012000282.1 YkgJ family cysteine cluster protein -
  SGO_RS04060 (SGO_0827) - 870726..871559 (+) 834 WP_012000283.1 AraC family transcriptional regulator -
  SGO_RS04065 (SGO_0828) - 871613..872539 (+) 927 WP_012000284.1 hypothetical protein -
  SGO_RS04070 (SGO_0829) - 872745..873434 (+) 690 WP_012000285.1 YjjG family noncanonical pyrimidine nucleotidase -
  SGO_RS04075 (SGO_0830) uvrC 873477..875312 (+) 1836 WP_012000286.1 excinuclease ABC subunit UvrC Machinery gene
  SGO_RS04080 - 875482..876027 (+) 546 WP_008808949.1 hypothetical protein -
  SGO_RS04085 (SGO_0833) - 876285..877130 (+) 846 WP_012000289.1 metallophosphoesterase family protein -
  SGO_RS04090 (SGO_0834) - 877137..878801 (+) 1665 WP_012000290.1 hypothetical protein -
  SGO_RS04095 (SGO_0835) - 878916..879521 (+) 606 WP_012000291.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 611 a.a.        Molecular weight: 70052.59 Da        Isoelectric Point: 9.0000

>NTDB_id=27058 SGO_RS04075 WP_012000286.1 873477..875312(+) (uvrC) [Streptococcus gordonii str. Challis substr. CH1]
MNKLIQSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNETYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRLFPFRKCTNPPEKVCF
YYHLGQCKAHTICQVDSQYFKDLAQEVAAFLKGQDDQIIEDLRGKMAGAAQTMEFEKAAEYRDLIQSIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYYNDPDEDFLTYIGQFYQEKSHLKPNEILIPADIDEEAVRAM
VDTKVLKPQRGEKKQLVNLAIKNARVSLQQKFDLLEKSIEKTQGAIENLGQLLNIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIKRRYSRVIRDGLTPPDLIVIDGGQGQVNVAKEVIQEQLGLDIPIAGLQ
KNDKHQTHELLFGDPLQVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGPKRKQNLMKHFKSL
TKIKEASVDEIVEVGVPRAVAEAVQEKLNLKTQEQQQARLREVAEPQAEIE

Nucleotide


Download         Length: 1836 bp        

>NTDB_id=27058 SGO_RS04075 WP_012000286.1 873477..875312(+) (uvrC) [Streptococcus gordonii str. Challis substr. CH1]
ATGAATAAGCTAATCCAATCAAAGCTGGAACTGTTGCCAACCAGTCCCGGCTGTTACATTCACAAAGATAAAAACGGTAC
TATTATTTATGTCGGAAAAGCCAAGAATCTTCGCAACCGGGTTCGTTCTTATTTCCGTGGTAGTCATGATACCAAGACGG
AGGCTTTGGTATCAGAGATTGTCGATTTTGAGTTTATTGTTACTGAGTCTAATATTGAGGCTTTGCTTCTGGAGATTAAT
CTAATCAAGGAAAACAAGCCCAAGTACAATATTATGCTCAAGGACGATAAGTCCTATCCTTTTATTAAGATTACCAATGA
AACCTATCCGCGCCTGATTATCACGCGCCAAGTCAAAAAGGATGGTGGGCTTTATTTTGGTCCCTACCCTGATGTCGGCG
CTGCCAATGAAATCAAGCGGCTTTTAGATCGACTCTTTCCTTTCCGTAAGTGTACCAATCCGCCTGAGAAAGTCTGCTTT
TACTACCATCTGGGCCAGTGCAAGGCCCACACTATTTGCCAGGTAGACAGCCAGTATTTCAAGGACTTGGCTCAGGAGGT
AGCGGCCTTTCTCAAAGGGCAGGATGACCAAATTATTGAGGATTTACGGGGAAAAATGGCTGGCGCAGCGCAAACTATGG
AATTTGAAAAGGCGGCGGAGTACCGCGACTTGATCCAGTCCATTGGCACCCTGCGAACCAAGCAGCGGGTCATGGCCAAG
GATTTGCAGAATCGAGATGTCTTTGGCTACTATGTGGACAAGGGCTGGATGTGCGTACAGGTCTTCTTTGTCCGCCAGGG
TAAGTTAATCGAGCGTGATGTCAATCTTTTTCCCTATTACAATGATCCGGACGAGGATTTCTTGACCTATATCGGCCAGT
TCTACCAGGAAAAATCCCACCTCAAGCCTAATGAAATTTTGATTCCGGCAGATATTGACGAAGAAGCTGTCCGAGCCATG
GTGGATACCAAGGTGCTTAAGCCTCAGCGAGGCGAGAAGAAGCAGCTGGTCAATCTGGCTATCAAAAACGCCCGAGTTAG
TCTCCAGCAGAAGTTTGACCTCTTGGAGAAATCAATTGAAAAGACTCAAGGTGCTATTGAGAATCTAGGGCAGCTCCTCA
ACATTCCGACGCCAGTTCGCATCGAGTCTTTTGATAACTCTAACATCATGGGGACCAGTCCTGTATCAGCTATGGTGGTC
TTTGTCAATGGTAAACCAAGCAAGAAGGACTATCGCAAGTATAAGATCAAGACTGTGGTAGGCCCGGATGACTACGCAAG
TATGCGTGAGGTCATCAAGCGGCGCTATAGTCGGGTGATTCGGGATGGACTGACTCCGCCTGATCTGATTGTTATTGACG
GTGGACAGGGCCAGGTTAATGTCGCTAAAGAAGTTATTCAGGAGCAGTTGGGATTGGACATTCCCATCGCTGGACTGCAA
AAAAATGACAAGCACCAGACTCATGAATTGCTTTTTGGTGACCCTCTGCAGGTTGTAGAATTATCCCGGAATTCGCAGGA
GTTTTTCCTACTCCAGCGTATCCAAGATGAAGTCCACCGCTTTGCTATTACCTTCCATCGCCAGCTCCGGTCTAAGAATT
CCTTCTCATCGCAGCTAGATGGTATCGAAGGATTGGGACCTAAGCGCAAGCAAAATCTCATGAAACACTTCAAATCTCTA
ACCAAGATTAAAGAAGCCAGCGTTGACGAAATTGTTGAAGTCGGCGTACCACGAGCAGTAGCCGAGGCAGTGCAGGAAAA
GTTGAATCTGAAAACTCAGGAGCAGCAACAAGCACGGTTGCGAGAGGTGGCAGAGCCACAAGCAGAAATAGAATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(197-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AWG9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

88.998

99.673

0.887
  uvrC Streptococcus pneumoniae D39

88.998

99.673

0.887
  uvrC Streptococcus pneumoniae TIGR4

91.511

96.399

0.882

Multiple sequence alignment