Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   A5904_RS13500 Genome accession   NZ_CP026328
Coordinates   2707073..2708440 (+) Length   455 a.a.
NCBI ID   WP_004869549.1    Uniprot ID   A0A059ZYE0
Organism   Acidithiobacillus caldus strain MTH-04     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2702073..2713440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A5904_RS13485 (A5904_13910) aroE 2702924..2703796 (+) 873 WP_004869542.1 shikimate dehydrogenase -
  A5904_RS13490 (A5904_13915) pilB 2703772..2705478 (+) 1707 WP_103415091.1 type IV-A pilus assembly ATPase PilB Machinery gene
  A5904_RS13495 (A5904_13920) - 2705523..2707076 (+) 1554 WP_070114588.1 sensor histidine kinase -
  A5904_RS13500 (A5904_13925) pilR 2707073..2708440 (+) 1368 WP_004869549.1 sigma-54-dependent transcriptional regulator Regulator
  A5904_RS13505 (A5904_13930) - 2708430..2709215 (+) 786 WP_004869552.1 prepilin peptidase -
  A5904_RS13510 (A5904_13935) coaE 2709234..2709821 (+) 588 WP_004869555.1 dephospho-CoA kinase -
  A5904_RS13515 (A5904_13940) zapD 2709926..2710678 (+) 753 WP_226823468.1 cell division protein ZapD -
  A5904_RS13520 (A5904_13945) - 2710690..2711697 (+) 1008 WP_004869560.1 class 1 fructose-bisphosphatase -
  A5904_RS13525 (A5904_13950) - 2711780..2712526 (-) 747 WP_014003617.1 complement resistance protein TraT -
  A5904_RS13530 (A5904_13955) - 2712672..2713097 (+) 426 WP_226047576.1 ClpXP protease specificity-enhancing factor -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 49960.73 Da        Isoelectric Point: 6.9080

>NTDB_id=268257 A5904_RS13500 WP_004869549.1 2707073..2708440(+) (pilR) [Acidithiobacillus caldus strain MTH-04]
MNASVRQRKRALIVDDEPTIVELLGITLEGMGVEVLACHSLAEAFAALGKGPPSLCLTDLRLGDGSGMQLLHKVRELYPQ
VPVAVITAYASAEGAVEAMRAGAFDFMTKPIELARLRRLVSEAIALGELPRESVDLSERLVGESPGMVALRERVRLLGRS
NAPVHIRGESGTGKELVARAIHDASPRREKAFIAVNCGAIPENLMESEFFGAEKGAYSGAVQRREGLFVAANGGTLFLDE
IAELPLTTQVKLLRVLQERVVRPLGGLREQSIDIRLICATHRDLRRMVEEGTFREDLFYRINVVPIEIPPLRERREDIPL
LAQTLLQRLCQRHGRPPANLAPAALAWLSNRDFPGNVRELENLLERALALQSQPLLHREDLEPTAELAVARAPLPAAAPA
ADTALTKRLAEAEWRYLADLQIRLGDRPEEMAKALGISLQSLHLRLARGGSNRDS

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=268257 A5904_RS13500 WP_004869549.1 2707073..2708440(+) (pilR) [Acidithiobacillus caldus strain MTH-04]
GTGAATGCCAGTGTTCGGCAAAGGAAACGGGCGCTCATCGTCGACGATGAGCCCACCATCGTGGAACTGCTGGGTATCAC
CTTGGAAGGCATGGGGGTCGAGGTCTTGGCTTGCCATAGCCTGGCCGAAGCCTTTGCCGCCCTGGGCAAGGGCCCACCAT
CGCTGTGCCTGACGGATCTGCGCCTGGGCGACGGCTCGGGCATGCAACTCCTGCACAAGGTCCGCGAACTCTACCCGCAG
GTGCCGGTGGCGGTGATCACCGCCTACGCCTCGGCGGAGGGCGCGGTGGAAGCCATGCGCGCCGGCGCCTTCGACTTCAT
GACCAAGCCCATAGAACTGGCACGTCTGCGCCGCCTGGTGAGCGAGGCCATCGCCCTTGGGGAGTTGCCCCGGGAGAGCG
TAGATCTCAGCGAGCGCCTGGTGGGCGAAAGCCCCGGCATGGTGGCCCTGCGCGAGCGCGTTCGCCTGCTGGGACGCAGC
AATGCACCGGTGCATATTCGCGGTGAATCGGGCACCGGCAAGGAACTGGTGGCCCGCGCCATACACGATGCAAGCCCACG
TCGGGAAAAGGCATTCATTGCCGTCAACTGCGGCGCCATCCCGGAAAATCTCATGGAGAGCGAGTTTTTTGGTGCCGAAA
AAGGTGCCTATTCCGGCGCCGTGCAACGGCGGGAAGGACTCTTCGTGGCAGCCAATGGTGGCACGCTCTTTCTCGACGAA
ATAGCCGAACTGCCGCTGACCACGCAGGTGAAACTGCTGCGGGTGCTGCAAGAGCGGGTGGTGCGACCGCTGGGTGGCCT
GCGCGAGCAGAGTATCGATATCCGCCTGATCTGTGCCACCCACCGCGATCTGCGCCGGATGGTGGAGGAGGGCACTTTTC
GCGAAGACCTCTTCTACCGCATCAATGTCGTACCCATAGAGATTCCGCCCCTGCGCGAACGCCGCGAGGACATCCCGCTA
CTGGCGCAAACGCTACTGCAGCGCCTCTGCCAGCGGCACGGACGTCCCCCGGCGAACCTCGCCCCCGCTGCGCTGGCCTG
GCTGTCCAACCGCGATTTCCCGGGCAACGTACGTGAGTTGGAGAACCTCCTGGAGCGGGCGCTCGCCCTACAGTCACAGC
CACTGCTGCACCGGGAAGATCTGGAGCCCACGGCGGAGCTCGCGGTGGCGCGGGCGCCACTGCCCGCTGCCGCACCCGCC
GCGGACACGGCCCTCACCAAGCGCCTGGCCGAGGCAGAGTGGCGCTATCTGGCCGACCTGCAGATCCGCCTTGGCGATCG
ACCCGAGGAAATGGCAAAGGCCCTGGGCATAAGCCTACAATCGCTCCATCTGCGTCTCGCCCGGGGAGGATCGAATCGTG
ATTCCTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(12-119)

Sigma-54 interaction domain (Sigma54_activat)

(140-307)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A059ZYE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

49.224

99.121

0.488
  pilR Acinetobacter baumannii strain A118

40.773

100

0.418

Multiple sequence alignment