Detailed information NTG0267499

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: DZS66_RS09085
• Genome accession: NZ_CP031627
• Coordinates: 1805203..1805970 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS28360
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1800203..1810970

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZS66_RS09070 (DZS66_09060)	hexB	1800721..1802703 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
DZS66_RS09075 (DZS66_09065)	-	1802798..1803949 (-)	1152	WP_003058754.1	site-specific integrase	-
DZS66_RS09900 (DZS66_09070)	-	1804198..1804341 (+)	144	WP_011185066.1	putative holin-like toxin	-
DZS66_RS09085 (DZS66_09075)	irvR	1805203..1805970 (-)	768	WP_003058809.1	S24 family peptidase	Regulator
DZS66_RS09090 (DZS66_09080)	-	1806124..1806330 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
DZS66_RS09095 (DZS66_09085)	-	1806364..1806537 (+)	174	Protein_1695	helix-turn-helix transcriptional regulator	-
DZS66_RS09100 (DZS66_09090)	-	1806585..1806992 (+)	408	WP_002992501.1	hypothetical protein	-
DZS66_RS09905	-	1807005..1807127 (+)	123	WP_011285272.1	hypothetical protein	-
DZS66_RS09105 (DZS66_09095)	-	1807410..1807931 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
DZS66_RS09110 (DZS66_09100)	-	1808179..1808352 (+)	174	WP_000132665.1	hypothetical protein	-
DZS66_RS09115 (DZS66_09105)	-	1808570..1808743 (+)	174	WP_000074663.1	hypothetical protein	-
DZS66_RS09120 (DZS66_09110)	-	1808905..1809336 (+)	432	WP_136302445.1	hypothetical protein	-
DZS66_RS09125 (DZS66_09115)	-	1809438..1809770 (+)	333	WP_011285276.1	hypothetical protein	-
DZS66_RS09130 (DZS66_09120)	-	1809770..1809961 (+)	192	WP_021340709.1	hypothetical protein	-
DZS66_RS09135 (DZS66_09125)	-	1809973..1810302 (+)	330	WP_003058810.1	hypothetical protein	-
DZS66_RS09140 (DZS66_09130)	-	1810305..1810577 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=267499 DZS66_RS09085 WP_003058809.1 1805203..1805970(-) (irvR) [Streptococcus pyogenes strain MGAS28360]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=267499 DZS66_RS09085 WP_003058809.1 1805203..1805970(-) (irvR) [Streptococcus pyogenes strain MGAS28360]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4