Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SPD_RS01870 Genome accession   NC_008533
Coordinates   348699..349388 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae D39     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 343699..354388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPD_RS01845 (SPD_0339) gpsB 343808..344137 (+) 330 WP_000146522.1 cell division regulator GpsB -
  SPD_RS01855 (SPD_0341) - 344623..345780 (+) 1158 WP_000711391.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  SPD_RS01860 (SPD_0342) mapZ 345793..347187 (+) 1395 WP_000039255.1 cell division site-positioning protein MapZ -
  SPD_RS01865 (SPD_0343) gndA 347263..348687 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  SPD_RS01870 (SPD_0344) covR 348699..349388 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  SPD_RS01875 (SPD_0345) cbpC 349486..350502 (+) 1017 WP_000771103.1 choline-binding protein CbpC -
  SPD_RS01880 (SPD_0346) mvk 350624..351502 (+) 879 WP_000163321.1 mevalonate kinase -
  SPD_RS01885 (SPD_0347) mvaD 351484..352437 (+) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  SPD_RS01890 (SPD_0348) - 352424..353431 (+) 1008 WP_000562411.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=26683 SPD_RS01870 WP_000518011.1 348699..349388(+) (covR) [Streptococcus pneumoniae D39]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=26683 SPD_RS01870 WP_000518011.1 348699..349388(+) (covR) [Streptococcus pneumoniae D39]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment