Detailed information NTG0266807

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RK67_RS09055
• Genome accession: NZ_CP026079
• Coordinates: 1739815..1740858 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_9
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1734815..1745858

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK67_RS09015 (RK67_009015)	-	1735241..1735351 (+)	111	WP_001790257.1	hypothetical protein	-
RK67_RS09020 (RK67_009020)	-	1735380..1735793 (+)	414	WP_001557448.1	hypothetical protein	-
RK67_RS09030 (RK67_009030)	-	1736224..1737210 (-)	987	WP_000999717.1	aromatic acid exporter family protein	-
RK67_RS09040 (RK67_009040)	map	1737741..1738499 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RK67_RS09045 (RK67_009045)	-	1738716..1739102 (+)	387	WP_001110179.1	hypothetical protein	-
RK67_RS09050 (RK67_009050)	liaF	1739117..1739818 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RK67_RS09055 (RK67_009055)	vraS	1739815..1740858 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RK67_RS09060 (RK67_009060)	vraR	1740848..1741477 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RK67_RS09065 (RK67_009065)	-	1741590..1742807 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
RK67_RS09070 (RK67_009070)	-	1743085..1743360 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
RK67_RS09075 (RK67_009075)	-	1743367..1743831 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RK67_RS09080 (RK67_009080)	-	1743978..1744178 (+)	201	WP_000180460.1	DUF1128 family protein	-
RK67_RS09085 (RK67_009085)	-	1744181..1745437 (+)	1257	WP_001795108.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=266807 RK67_RS09055 WP_001017131.1 1739815..1740858(+) (vraS) [Staphylococcus aureus strain FDAARGOS_9]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=266807 RK67_RS09055 WP_001017131.1 1739815..1740858(+) (vraS) [Staphylococcus aureus strain FDAARGOS_9]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1