Detailed information NTG0266789

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RK65_RS13555
• Genome accession: NZ_CP026077
• Coordinates: 2632533..2633576 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_7
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2627533..2638576

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK65_RS13525 (RK65_013525)	-	2627951..2629207 (-)	1257	WP_001795438.1	aminopeptidase	-
RK65_RS13530 (RK65_013530)	-	2629210..2629410 (-)	201	WP_000180461.1	DUF1128 family protein	-
RK65_RS13535 (RK65_013535)	-	2629557..2630021 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RK65_RS13540 (RK65_013540)	-	2630028..2630303 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
RK65_RS13545 (RK65_013545)	-	2630581..2631798 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
RK65_RS13550 (RK65_013550)	vraR	2631914..2632543 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
RK65_RS13555 (RK65_013555)	vraS	2632533..2633576 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RK65_RS13560 (RK65_013560)	liaF	2633573..2634274 (-)	702	WP_047211910.1	cell wall-active antibiotics response protein LiaF	-
RK65_RS13565 (RK65_013565)	-	2634289..2634675 (-)	387	WP_001110179.1	hypothetical protein	-
RK65_RS13570 (RK65_013570)	map	2634892..2635650 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RK65_RS13585 (RK65_013585)	-	2636178..2637164 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
RK65_RS13595 (RK65_013595)	-	2637595..2638008 (-)	414	WP_001549145.1	hypothetical protein	-
RK65_RS13600 (RK65_013600)	-	2638037..2638147 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=266789 RK65_RS13555 WP_001017131.1 2632533..2633576(-) (vraS) [Staphylococcus aureus strain FDAARGOS_7]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=266789 RK65_RS13555 WP_001017131.1 2632533..2633576(-) (vraS) [Staphylococcus aureus strain FDAARGOS_7]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1