Detailed information NTG0266716

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RK63_RS04525
• Genome accession: NZ_CP026076
• Coordinates: 797226..798113 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_4
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 792226..803113

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK63_RS04490 (RK63_004490)	-	792245..792337 (+)	93	WP_010956583.1	hypothetical protein	-
RK63_RS04495 (RK63_004495)	-	792445..792942 (-)	498	WP_001065268.1	glutathione peroxidase	-
RK63_RS04500 (RK63_004500)	-	792952..793212 (-)	261	WP_001789910.1	hypothetical protein	-
RK63_RS04510 (RK63_004510)	-	793594..793707 (-)	114	WP_001791776.1	hypothetical protein	-
RK63_RS04515 (RK63_004515)	-	794366..796366 (-)	2001	WP_000776751.1	ABC transporter permease	-
RK63_RS04520 (RK63_004520)	-	796363..797118 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RK63_RS04525 (RK63_004525)	braS	797226..798113 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RK63_RS04530 (RK63_004530)	braR	798124..798789 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RK63_RS04535 (RK63_004535)	-	798815..799015 (-)	201	WP_000604728.1	hypothetical protein	-
RK63_RS04540 (RK63_004540)	-	799213..800637 (+)	1425	WP_000953744.1	alkaline phosphatase	-
RK63_RS14970 (RK63_004545)	-	800697..800798 (-)	102	WP_000731972.1	SE2200 family small protein	-
RK63_RS04550 (RK63_004550)	-	800920..801375 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RK63_RS04555 (RK63_004555)	-	801620..802381 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=266716 RK63_RS04525 WP_000143419.1 797226..798113(-) (braS) [Staphylococcus aureus strain FDAARGOS_4]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=266716 RK63_RS04525 WP_000143419.1 797226..798113(-) (braS) [Staphylococcus aureus strain FDAARGOS_4]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997