Detailed information NTG0266513

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RK85_RS05720
• Genome accession: NZ_CP026070
• Coordinates: 1139030..1139917 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_27
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1134030..1144917

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK85_RS05690 (RK85_005690)	-	1134762..1135523 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
RK85_RS05695 (RK85_005695)	-	1135768..1136223 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RK85_RS14450 (RK85_005700)	-	1136345..1136446 (+)	102	WP_000731972.1	SE2200 family small protein	-
RK85_RS05705 (RK85_005705)	-	1136506..1137930 (-)	1425	WP_000953744.1	alkaline phosphatase	-
RK85_RS05710 (RK85_005710)	-	1138128..1138328 (+)	201	WP_000604728.1	hypothetical protein	-
RK85_RS05715 (RK85_005715)	braR	1138354..1139019 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RK85_RS05720 (RK85_005720)	braS	1139030..1139917 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RK85_RS05725 (RK85_005725)	-	1140025..1140780 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RK85_RS05730 (RK85_005730)	-	1140777..1142777 (+)	2001	WP_000776751.1	ABC transporter permease	-
RK85_RS05735 (RK85_005735)	-	1143436..1143549 (+)	114	WP_011447078.1	hypothetical protein	-
RK85_RS05745 (RK85_005745)	-	1143931..1144191 (+)	261	WP_001789910.1	hypothetical protein	-
RK85_RS05750 (RK85_005750)	-	1144201..1144698 (+)	498	WP_001065268.1	glutathione peroxidase	-
RK85_RS05755 (RK85_005755)	-	1144806..1144898 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=266513 RK85_RS05720 WP_000143419.1 1139030..1139917(+) (braS) [Staphylococcus aureus strain FDAARGOS_27]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=266513 RK85_RS05720 WP_000143419.1 1139030..1139917(+) (braS) [Staphylococcus aureus strain FDAARGOS_27]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997