Detailed information NTG0266492

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: RK83_RS12920
• Genome accession: NZ_CP026069
• Coordinates: 2502118..2503104 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain FDAARGOS_25
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 2497118..2508104

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK83_RS12895 (RK83_012895)	-	2497378..2497725 (-)	348	WP_001242103.1	hypothetical protein	-
RK83_RS12900 (RK83_012900)	-	2497911..2498504 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
RK83_RS12905 (RK83_012905)	-	2498608..2498973 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
RK83_RS12910 (RK83_012910)	yjbH	2498996..2499802 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
RK83_RS12915 (RK83_012915)	pepF	2500262..2502070 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
RK83_RS12920 (RK83_012920)	coiA	2502118..2503104 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
RK83_RS12925 (RK83_012925)	mecA	2503225..2503944 (-)	720	WP_001217728.1	adaptor protein MecA	-
RK83_RS12930 (RK83_012930)	spxA	2504315..2504710 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
RK83_RS12935 (RK83_012935)	trpS	2505004..2505993 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
RK83_RS12940 (RK83_012940)	opp4C	2506035..2506916 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
RK83_RS12945 (RK83_012945)	opp4B	2506928..2507890 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=266492 RK83_RS12920 WP_000959282.1 2502118..2503104(-) (coiA) [Staphylococcus aureus strain FDAARGOS_25]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=266492 RK83_RS12920 WP_000959282.1 2502118..2503104(-) (coiA) [Staphylococcus aureus strain FDAARGOS_25]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976