Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   DS732_RS15350 Genome accession   NZ_CP031546
Coordinates   2988344..2989000 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain cq9     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2983344..2994000
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DS732_RS15320 (DS732_15320) yecA 2984595..2985260 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  DS732_RS15340 (DS732_15340) pgsA 2985910..2986458 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  DS732_RS15345 (DS732_15345) uvrC 2986515..2988347 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  DS732_RS15350 (DS732_15350) letA 2988344..2989000 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  DS732_RS32695 - 2989142..2989213 (+) 72 Protein_2834 transcriptional regulator -
  DS732_RS31650 yecU 2989296..2989472 (+) 177 WP_000590347.1 protein YecU -
  DS732_RS15355 (DS732_15355) yecF 2989459..2989683 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  DS732_RS15360 (DS732_15360) sdiA 2989750..2990472 (-) 723 WP_001154276.1 transcriptional regulator SdiA -
  DS732_RS15365 (DS732_15365) tcyN 2990702..2991454 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  DS732_RS15370 (DS732_15370) tcyL 2991451..2992119 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  DS732_RS15375 (DS732_15375) dcyD 2992134..2993120 (-) 987 WP_001128238.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=266274 DS732_RS15350 WP_000611335.1 2988344..2989000(-) (letA) [Escherichia coli strain cq9]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=266274 DS732_RS15350 WP_000611335.1 2988344..2989000(-) (letA) [Escherichia coli strain cq9]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAACGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment