Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF   Type   Machinery gene
Locus tag   LACR_RS11710 Genome accession   NC_008527
Coordinates   2248201..2248647 (-) Length   148 a.a.
NCBI ID   WP_041167483.1    Uniprot ID   A0AA34TLJ2
Organism   Lactococcus cremoris subsp. cremoris SK11     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2243338..2251446 2248201..2248647 within 0


Gene organization within MGE regions


Location: 2243338..2251446
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LACR_RS11685 (LACR_2417) - 2244804..2245613 (-) 810 WP_011677177.1 metal ABC transporter permease -
  LACR_RS11690 (LACR_2418) - 2245606..2246343 (-) 738 WP_011677178.1 metal ABC transporter ATP-binding protein -
  LACR_RS11695 (LACR_2419) - 2246522..2247364 (-) 843 WP_011677179.1 metal ABC transporter solute-binding protein, Zn/Mn family -
  LACR_RS11700 (LACR_2420) - 2247361..2247798 (-) 438 WP_011677180.1 zinc-dependent MarR family transcriptional regulator -
  LACR_RS11705 (LACR_2421) comGG 2247878..2248177 (-) 300 WP_011677181.1 competence type IV pilus minor pilin ComGG Machinery gene
  LACR_RS11710 (LACR_2422) comGF 2248201..2248647 (-) 447 WP_041167483.1 competence type IV pilus minor pilin ComGF Machinery gene
  LACR_RS11715 (LACR_2423) comGE 2248610..2248906 (-) 297 WP_011677183.1 competence type IV pilus minor pilin ComGE Machinery gene
  LACR_RS14670 (LACR_2424) comGD 2248878..2249066 (-) 189 WP_014573336.1 hypothetical protein Machinery gene
  LACR_RS11725 (LACR_2425) comGC 2249268..2249618 (-) 351 WP_050574401.1 competence type IV pilus major pilin ComGC Machinery gene
  LACR_RS11730 (LACR_2426) comGB 2249663..2250689 (-) 1027 Protein_2284 competence type IV pilus assembly protein ComGB -
  LACR_RS11735 - 2250589..2251410 (-) 822 Protein_2285 ATPase, T2SS/T4P/T4SS family -

Sequence

Protein


Download         Length: 148 a.a.        Molecular weight: 17086.77 Da        Isoelectric Point: 8.2376

>NTDB_id=26580 LACR_RS11710 WP_041167483.1 2248201..2248647(-) (comGF) [Lactococcus cremoris subsp. cremoris SK11]
MERKFCDLKLKIRAFTLLECLVALLAISGSVPVISGLTRMIEEQMKISQNDSRKDWQIFCEQMRSELSGAKLDNVNQNFL
YVTKDKKLRFGLVGDDFRKSDDKGQGYQPMLYDLKGAKIQAEENLIKITIDFDNGGERVFIYRFTDTK

Nucleotide


Download         Length: 447 bp        

>NTDB_id=26580 LACR_RS11710 WP_041167483.1 2248201..2248647(-) (comGF) [Lactococcus cremoris subsp. cremoris SK11]
ATGGAAAGGAAATTTTGCGACTTGAAGCTCAAAATTAGGGCATTTACTTTACTTGAATGTCTCGTAGCACTTTTGGCAAT
TTCTGGTTCAGTGCCAGTCATCTCAGGGCTGACTAGAATGATTGAAGAACAGATGAAAATAAGCCAGAATGATAGTAGGA
AAGATTGGCAAATATTTTGTGAACAAATGCGTTCAGAACTCTCCGGAGCAAAATTAGACAATGTGAATCAAAATTTTTTG
TATGTGACCAAAGATAAGAAGTTACGGTTCGGATTAGTAGGGGATGATTTTCGTAAAAGTGATGATAAAGGGCAAGGATA
CCAACCGATGCTTTATGATTTAAAAGGAGCAAAAATTCAGGCAGAAGAAAATTTGATAAAAATAACAATTGATTTTGATA
ATGGAGGTGAGCGAGTATTTATTTATCGATTTACTGATACAAAGTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(45-137)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF Lactococcus lactis subsp. cremoris KW2

98.582

95.27

0.939
  comYF Streptococcus mutans UA140

44.681

95.27

0.426
  comYF Streptococcus mutans UA159

43.972

95.27

0.419
  comGF/cglF Streptococcus mitis SK321

38.571

94.595

0.365
  comGF/cglF Streptococcus mitis NCTC 12261

38.571

94.595

0.365

Multiple sequence alignment