Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BS11774_RS12235 Genome accession   NZ_CP026010
Coordinates   2331871..2332527 (+) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus subtilis strain ATCC 11774     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2326871..2337527
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BS11774_RS12205 (BS11774_12155) oppF 2327124..2328041 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  BS11774_RS12210 (BS11774_12160) yjbB 2328147..2329364 (+) 1218 WP_128473813.1 MFS transporter -
  BS11774_RS12215 (BS11774_12165) yjbC 2329529..2330107 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  BS11774_RS12220 (BS11774_12170) spx 2330288..2330683 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  BS11774_RS12225 (BS11774_12175) yjbE 2330938..2331594 (-) 657 WP_014479447.1 TerC family protein -
  BS11774_RS12230 - 2331764..2331904 (+) 141 WP_119122854.1 hypothetical protein -
  BS11774_RS12235 (BS11774_12180) mecA 2331871..2332527 (+) 657 WP_014479448.1 adaptor protein MecA Regulator
  BS11774_RS12240 - 2332522..2332644 (-) 123 WP_128473814.1 hypothetical protein -
  BS11774_RS12245 (BS11774_12185) coiA 2332718..2333839 (+) 1122 WP_250634914.1 competence protein CoiA Machinery gene
  BS11774_RS12250 (BS11774_12190) pepF 2334069..2335898 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  BS11774_RS12255 (BS11774_12195) - 2335935..2336102 (-) 168 WP_003244944.1 hypothetical protein -
  BS11774_RS12265 (BS11774_12205) spxH 2336417..2337316 (-) 900 WP_041340381.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=264987 BS11774_RS12235 WP_014479448.1 2331871..2332527(+) (mecA) [Bacillus subtilis strain ATCC 11774]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=264987 BS11774_RS12235 WP_014479448.1 2331871..2332527(+) (mecA) [Bacillus subtilis strain ATCC 11774]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995

Multiple sequence alignment