Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DV130_RS05830 Genome accession   NZ_CP031248
Coordinates   1115282..1115914 (-) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain M26365     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1110282..1120914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV130_RS05795 tig 1111325..1112608 (-) 1284 WP_000116462.1 trigger factor -
  DV130_RS05800 - 1112802..1113107 (-) 306 WP_001821501.1 tyrosine-type recombinase/integrase -
  DV130_RS05805 cbpG 1113463..1114053 (-) 591 Protein_1126 choline-binding protein CbpG -
  DV130_RS05810 - 1114134..1114373 (-) 240 WP_000754502.1 hypothetical protein -
  DV130_RS12475 - 1114523..1115281 (-) 759 Protein_1128 DNA alkylation repair protein -
  DV130_RS05830 vraR 1115282..1115914 (-) 633 WP_000698434.1 response regulator transcription factor Regulator
  DV130_RS05835 - 1115928..1116923 (-) 996 WP_000743663.1 sensor histidine kinase -
  DV130_RS05840 liaF 1116920..1117618 (-) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  DV130_RS05845 fni 1117696..1118706 (-) 1011 WP_050088102.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  DV130_RS05850 - 1118690..1119697 (-) 1008 WP_000562417.1 phosphomevalonate kinase -
  DV130_RS05855 mvaD 1119684..1120637 (-) 954 WP_000373458.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=263372 DV130_RS05830 WP_000698434.1 1115282..1115914(-) (vraR) [Streptococcus pneumoniae strain M26365]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=263372 DV130_RS05830 WP_000698434.1 1115282..1115914(-) (vraR) [Streptococcus pneumoniae strain M26365]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCGGATGTTATTGTTATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTACGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment