Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   DV129_RS11395 Genome accession   NZ_CP031247
Coordinates   2072743..2073420 (+) Length   225 a.a.
NCBI ID   WP_000548991.1    Uniprot ID   A0A501PEF7
Organism   Streptococcus pneumoniae strain M23734     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2067743..2078420
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS11360 - 2068091..2068738 (-) 648 WP_000260188.1 nicotinamide mononucleotide transporter -
  DV129_RS12670 - 2068764..2068955 (-) 192 WP_001846744.1 hypothetical protein -
  DV129_RS11370 - 2068936..2069586 (-) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  DV129_RS11375 - 2069698..2070540 (+) 843 WP_000160940.1 metallophosphoesterase family protein -
  DV129_RS11380 - 2070616..2071053 (+) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  DV129_RS11385 - 2071121..2071423 (+) 303 WP_000281608.1 hypothetical protein -
  DV129_RS11390 - 2071514..2072587 (-) 1074 WP_001273814.1 DUF2974 domain-containing protein -
  DV129_RS11395 braR 2072743..2073420 (+) 678 WP_000548991.1 response regulator transcription factor Regulator
  DV129_RS11400 - 2073413..2074387 (+) 975 WP_000887955.1 HAMP domain-containing histidine kinase -
  DV129_RS11405 thrS 2074436..2076379 (-) 1944 WP_000608339.1 threonine--tRNA ligase -
  DV129_RS11410 - 2076437..2076760 (-) 324 WP_000422779.1 MazG-like protein -
  DV129_RS12435 - 2077017..2077380 (-) 364 Protein_2098 hypothetical protein -
  DV129_RS11430 - 2077619..2078248 (+) 630 WP_000762092.1 NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25936.11 Da        Isoelectric Point: 5.1362

>NTDB_id=263326 DV129_RS11395 WP_000548991.1 2072743..2073420(+) (braR) [Streptococcus pneumoniae strain M23734]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=263326 DV129_RS11395 WP_000548991.1 2072743..2073420(+) (braR) [Streptococcus pneumoniae strain M23734]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A501PEF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369