Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DV129_RS05910 Genome accession   NZ_CP031247
Coordinates   1104924..1105556 (-) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain M23734     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1099924..1110556
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS05875 tig 1100956..1102239 (-) 1284 WP_000116465.1 trigger factor -
  DV129_RS05880 - 1102400..1102738 (-) 339 WP_001812733.1 tyrosine-type recombinase/integrase -
  DV129_RS05885 cbpG 1103094..1103684 (-) 591 Protein_1114 choline-binding protein CbpG -
  DV129_RS05890 - 1103765..1104004 (-) 240 WP_000754501.1 hypothetical protein -
  DV129_RS12215 - 1104154..1104759 (-) 606 Protein_1116 DNA alkylation repair protein -
  DV129_RS05905 - 1104681..1104923 (-) 243 WP_001808881.1 DNA alkylation repair protein -
  DV129_RS05910 vraR 1104924..1105556 (-) 633 WP_000698434.1 response regulator transcription factor Regulator
  DV129_RS05915 - 1105570..1106565 (-) 996 WP_000743661.1 sensor histidine kinase -
  DV129_RS05920 liaF 1106562..1107260 (-) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  DV129_RS05925 fni 1107337..1108347 (-) 1011 WP_000210617.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  DV129_RS05930 - 1108331..1109338 (-) 1008 WP_000562430.1 phosphomevalonate kinase -
  DV129_RS05935 mvaD 1109325..1110278 (-) 954 WP_000373458.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=263256 DV129_RS05910 WP_000698434.1 1104924..1105556(-) (vraR) [Streptococcus pneumoniae strain M23734]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=263256 DV129_RS05910 WP_000698434.1 1104924..1105556(-) (vraR) [Streptococcus pneumoniae strain M23734]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41