Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   DV131_RS10875 Genome accession   NZ_CP031246
Coordinates   2040036..2040713 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain M26368     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2035036..2045713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV131_RS10840 - 2035197..2035826 (-) 630 WP_000762083.1 NAD(P)-dependent oxidoreductase -
  DV131_RS10845 - 2036065..2036265 (+) 201 WP_162797630.1 hypothetical protein -
  DV131_RS10860 - 2036696..2037019 (+) 324 WP_000422779.1 MazG-like protein -
  DV131_RS10865 thrS 2037077..2039020 (+) 1944 WP_000608356.1 threonine--tRNA ligase -
  DV131_RS10870 - 2039069..2040043 (-) 975 WP_000887954.1 HAMP domain-containing histidine kinase -
  DV131_RS10875 braR 2040036..2040713 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  DV131_RS10880 - 2040869..2041942 (+) 1074 WP_001273828.1 DUF2974 domain-containing protein -
  DV131_RS10885 - 2042033..2042336 (-) 304 Protein_2031 hypothetical protein -
  DV131_RS10890 - 2042405..2042842 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  DV131_RS10895 - 2042918..2043760 (-) 843 WP_000160943.1 metallophosphoesterase family protein -
  DV131_RS10900 - 2043872..2044522 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  DV131_RS10910 - 2044699..2045343 (+) 645 WP_114865946.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=263203 DV131_RS10875 WP_000548959.1 2040036..2040713(-) (braR) [Streptococcus pneumoniae strain M26368]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=263203 DV131_RS10875 WP_000548959.1 2040036..2040713(-) (braR) [Streptococcus pneumoniae strain M26368]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369