Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SSA_RS09025 Genome accession   NC_009009
Coordinates   1835952..1836584 (-) Length   210 a.a.
NCBI ID   WP_002893493.1    Uniprot ID   A3CPW8
Organism   Streptococcus sanguinis SK36     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1830952..1841584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS09000 (SSA_1836) comFA/cflA 1831028..1832326 (-) 1299 WP_011837400.1 DEAD/DEAH box helicase Machinery gene
  SSA_RS09005 (SSA_1837) - 1832383..1833015 (+) 633 WP_011837401.1 YigZ family protein -
  SSA_RS09010 (SSA_1839) cysK 1833116..1834045 (+) 930 WP_002893488.1 cysteine synthase A -
  SSA_RS09015 (SSA_1840) - 1834150..1834512 (-) 363 WP_002901252.1 S1 RNA-binding domain-containing protein -
  SSA_RS09020 (SSA_1841) - 1834512..1835912 (-) 1401 WP_011837402.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SSA_RS09025 (SSA_1842) vraR 1835952..1836584 (-) 633 WP_002893493.1 response regulator transcription factor Regulator
  SSA_RS09030 (SSA_1843) - 1836562..1837581 (-) 1020 WP_002893495.1 sensor histidine kinase -
  SSA_RS09035 (SSA_1844) liaF 1837578..1838273 (-) 696 WP_002893496.1 cell wall-active antibiotics response protein LiaF -
  SSA_RS09040 (SSA_1845) stkP 1838418..1840271 (-) 1854 WP_011837403.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SSA_RS09045 (SSA_1846) - 1840268..1841008 (-) 741 WP_002896965.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23763.40 Da        Isoelectric Point: 5.0460

>NTDB_id=26320 SSA_RS09025 WP_002893493.1 1835952..1836584(-) (vraR) [Streptococcus sanguinis SK36]
MKILLVDDHQMVRLGLKSYLELQEDIAEVSEAVNGKEGVEKALASRPDVIIMDIVMPEMNGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAHGYMLKTSSAEEILRAVKKVAKGEFAIETEVSKKVEYHRNHIELHEDLTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=26320 SSA_RS09025 WP_002893493.1 1835952..1836584(-) (vraR) [Streptococcus sanguinis SK36]
ATGAAGATATTGTTAGTGGATGACCATCAGATGGTCAGATTGGGATTGAAAAGTTATCTGGAACTGCAAGAGGATATAGC
AGAGGTATCCGAAGCAGTTAATGGCAAAGAAGGTGTGGAGAAGGCTTTGGCAAGTCGTCCGGATGTGATTATCATGGATA
TCGTCATGCCTGAGATGAATGGGATTGAAGCGACACTGGCCATTTTAAAGGAGTGGCCGGAAGCAAAGATTCTGATTTTG
ACTTCTTATTTGGATAATGAAAAAATTTATCCTGTTCTGGATGCAGGCGCTCATGGATACATGCTCAAGACTTCCAGCGC
TGAAGAAATTCTTCGTGCCGTCAAAAAAGTGGCCAAGGGAGAATTTGCCATTGAAACAGAGGTCAGCAAGAAAGTGGAGT
ACCATCGTAACCATATCGAACTCCATGAGGATTTGACAGCTCGTGAGCGTGATATTTTAGGGCTTTTGGCCAAGGGTTAT
GAAAATCAACGGATTGCAGATGAGCTCTTCATTTCCCTCAAAACGGTCAAGACTCATGTCTCCAATATCCTGTCCAAATT
GGAGGTGAGCGACCGCACGCAGGCAGTTGTTTATGCTTTTCAGCACCATCTTGTCCCACAAGAAGACTTTTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3CPW8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.398

98.095

0.524
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414

Multiple sequence alignment